Research Articles Library
Literature Analysis Tools
Advanced Search
Filter by PMID, year, source, DOI and other criteria
Literature Analysis
Analyze research trends and hotspots
Batch Export
Export search results to Excel/PDF
Efficacy and safety of dual-targeted therapy for inflammatory bowel disease: a retrospective multicenter study in China
Publication Year: 2025 Source: Therap Adv Gastroenterol PMID: 39758966 DOI: 10.1177/17562848241307598
BACKGROUND: Treatment options for patients with refractory inflammatory bowel disease (IBD) or concomitant IBD and extraintestinal manifestations (EIM) are often limited. OBJECTIVE: This study aimed to examine the efficacy and safety of combining biologics or small molecules in patients with refractory IBD, active EIM, or active immune-mediated inflammatory disease (IMID). …
Increased gastrointestinal bleeding-related mortality during the COVID-19 pandemic
Publication Year: 2025 Source: Therap Adv Gastroenterol PMID: 39758969
BACKGROUND: Despite its significant health burden, there is a lack of national-level temporal patterns in gastrointestinal bleeding (GIB) mortality. OBJECTIVES: To comprehensively decipher the annual and monthly trend of GIB-related mortality in the United States. DESIGN: Cross-sectional study. METHODS: We analyzed the National Vital Statistic System database, which documents more …
Advancements in dual biologic therapy for inflammatory bowel diseases: efficacy, safety, and future directions
Publication Year: 2025 Source: Therap Adv Gastroenterol PMID: 39758970 DOI: 10.1177/17562848241309871
Inflammatory bowel diseases (IBDs), primarily encompassing ulcerative colitis and Crohn's disease, represent a challenging spectrum of disorders with a multifaceted pathogenesis. Despite the array of available treatments, a demand for novel therapeutic options persists to achieve remission in a broader patient population. Research findings indicate that relying solely on a …
Gender-Affirming Vaginoplasty in a Patient With Inflammatory Bowel Disease
Publication Year: 2025 Source: Urogynecology (Phila) PMID: 39760190
No Abstract
Prevalence and Risk Factors of Spondyloarthritis Symptoms in a US-Based Multicenter Cohort of Patients With Inflammatory Bowel Disease
Publication Year: 2025 Source: Am J Gastroenterol PMID: 39760386 DOI: 10.14309/ajg.0000000000003292
INTRODUCTION: Spondyloarthritis (SpA), the most common extraintestinal manifestation of inflammatory bowel disease (IBD), is reported in up to 39% of patients with IBD. Despite this high prevalence, risk factors of developing SpA in patients with IBD are not well described. In this study, we aimed to determine the factors associated …
Obesity and Chronic Inflammation: Implications for Rheumatoid Arthritis, Spondyloarthritis, and Ulcerative Colitis
Publication Year: 2025 Source: Immun Inflamm Dis PMID: 39760506 DOI: 10.1002/iid3.70080
BACKGROUND: Immune-mediated inflammatory diseases (IMIDs) are a group of chronic conditions characterized by dysregulated immune responses and persistent inflammation. Rheumatoid arthritis (RA), spondyloarthritis (SpA), and ulcerative colitis (UC) exemplify prominent IMIDs, each presenting unique challenges for their management, that impact patient's quality of life (QoL). Obesity, marked by persistent low-grade …
Modulating the microbiome in chronic liver diseases - current evidence on the role of fecal microbiota transplantation
Publication Year: 2025 Source: Expert Rev Gastroenterol Hepatol PMID: 39760535
INTRODUCTION: The gut microbiota has a complex relationship with the human host and is key to maintaining health. Disruption of the healthy diverse gut microbial milieu plays an important role in the pathogenesis of several diseases including Clostridioides difficile infection (CDI), inflammatory bowel disease, irritable bowel syndrome, alcohol-related liver disease …
Inpatient Nutritional Considerations in Inflammatory Bowel Disease
Publication Year: 2025 Source: Curr Gastroenterol Rep PMID: 39760825 DOI: 10.1007/s11894-024-00958-0
PURPOSE OF REVIEW: This review aims to explain the causes, diagnosis, and treatment of malnutrition in hospitalized patients with inflammatory bowel disease (IBD), focusing on both adults and children. RECENT FINDINGS: Malnutrition is common among IBD patients, affecting up to 85% of individuals, and is linked to higher rates of …
Effects of immune cells in mediating the relationship between inflammatory bowel disease and pyoderma gangrenosum: a two-sample, two-step mendelian randomization study
Publication Year: 2025 Source: Arch Dermatol Res PMID: 39760889 DOI: 10.1007/s00403-024-03736-0
BACKGROUND: Although the precise cause of the co-occurrence of pyoderma gangrenosum (PG) and inflammatory bowel disease (IBD) is still unknown, prior research has shown that the two conditions coexist. Moreover, it is currently unknown how immune cells function in influencing the relationship between IBD and PG. METHODS: In order to …
Radiation exposure in patients with inflammatory bowel disease
Publication Year: 2025 Source: J Crohns Colitis PMID: 39761345 DOI: 10.1093/ecco-jcc/jjaf001
BACKGROUND AND AIMS: Radiological imaging is crucial for diagnosing and monitoring patients with inflammatory bowel diseases (IBD). With increasing awareness of radiation risks, imaging doses should be "as low as reasonably achievable," with a risk level that one should try to stay underneath 75 mSv. However, real-world data on cumulative …
Need more literature?
The current database contains 98453 research articles. If you need to search for more literature or perform AI analysis, please use our knowledge acquisition module or explore external literature resources.
External Resources: Access comprehensive literature databases worldwide