Research Articles Library
Literature Analysis Tools
Advanced Search
Filter by PMID, year, source, DOI and other criteria
Literature Analysis
Analyze research trends and hotspots
Batch Export
Export search results to Excel/PDF
Case report and literature review of gallbladder paraganglioma in patient with inflammatory bowel disease
Publication Year: 2025 Source: J Surg Case Rep PMID: 40585934
Primary paraganglioma of the gallbladder is an extremely rare pathology. Only 21 cases have been reported in the literature, and we present the first reported case of gallbladder paraganglioma in a patient with inflammatory bowel disease and primary sclerosing cholangitis. A 54-year-old lady with history of chronic right upper quadrant …
Inflammatory Bowel Disease Induces Colorectal Cancer: Risk Factors, Triggering Mechanisms, and Treatment With Phyto-Derivatives
Publication Year: 2025 Source: Phytother Res PMID: 40586116 DOI: 10.1002/ptr.70015
Colorectal cancer (CRC), one of the most prevalent malignant neoplasms, ranks as a leading cause of cancer-related mortality on a global scale. A particularly aggressive variant of CRC is colitis-associated colon cancer (CAC). Patients with chronic inflammatory bowel disease (IBD) are at increased risk for CAC. The pathogenesis of CAC …
Retention rate and predictor factors of drug discontinuation in axial spondyloarthritis: a focus on certolizumab and secukinumab
Publication Year: 2025 Source: Reumatismo PMID: 40586484
OBJECTIVE: Drug survival rate and time are important to demonstrate the effectiveness of treatment in patients with axial spondyloarthritis (axSpA) in real life. Therefore, we aimed to evaluate drug survival rate and predictors of discontinuation of certolizumab and secukinumab in axSpA patients. METHODS: This single-center retrospective cohort study included patients …
The Impact of the Shift in Clinical Management From Reactive to Preventative on the Rate of Bowel Resection in Inflammatory Bowel Disease Within a Large Health Care Organization
Publication Year: 2025 Source: Am Surg PMID: 40586667 DOI: 10.1177/00031348251355934
BackgroundThe advent of biologic therapy has been used as a surrogate marker for the shift from reactive to preventative management and surveillance for inflammatory bowel disease (IBD). This shift has resulted in earlier detection, earlier medical therapy, and increased bowel preservation in many published series.MethodsA retrospective population-based study was conducted …
Deep Characterisation of Circulating Torque Teno Virus DNA Load in Crohn's Disease Patients
Publication Year: 2025 Source: J Med Virol PMID: 40586686
Torque teno virus (TTV) DNA load in plasma is suggested as a marker for immunosuppression post-transplantation. Crohn's disease (CD) arises from genetic susceptibility, environmental factors, and dysbiosis, causing immune responses. This study examines TTV DNA load in CD patients in remission and its correlation with relapse. Using quantitative real-time polymerase …
Aptamer-Amplified and CRISPR-Cas12a-Assisted Dual-Mode PEC-SERS Biosensor for Ultrasensitive Detection of Inflammatory Bowel Disease Biomarkers
Publication Year: 2025 Source: Anal Chem PMID: 40586733 DOI: 10.1021/acs.analchem.5c01481
Inflammatory bowel disease (IBD) has proven to be a critical global health problem characterized by severe life-threatening complications; thus, the development of noninvasive, reliable, and cost-effective diagnostic methods remains an urgent clinical need. Herein, a novel photoelectrochemical (PEC) and surface-enhanced Raman scattering (SERS) dual-mode platform was successfully developed for ultrasensitive …
CD131 contributes to ulcerative colitis pathogenesis by promoting macrophage infiltration
Publication Year: 2025 Source: Elife PMID: 40586774
BACKGROUND: Ulcerative colitis (UC) is a group of chronic inflammatory bowel disease mainly affecting the colon. The exact etiology of UC remains elusive. CD131 is a receptor subunit mediating the effects of hematopoietic growth factors granulocyte-macrophage colony-stimulating factor (GM-CSF) and Interleukin-3 (IL-3), which regulate various inflammatory responses. The pleiotropic effects …
[Monoclonal antibodies in patients with chronic inflammatory bowel diseases]
Publication Year: 2025 Source: Inn Med (Heidelb) PMID: 40586813
No Abstract
ATF7-PINK1 Axis Governs Mitophagy and Intestinal Inflammation in Ulcerative Colitis
Publication Year: 2025 Source: FASEB J PMID: 40586859
Ulcerative colitis (UC), a chronic inflammatory bowel disease, is marked by sustained inflammation and excessive apoptosis of intestinal epithelial cells (IECs). Despite progress in understanding UC pathogenesis, the role of activating transcription factors (ATFs) in disease progression remains elusive. Here, we profile the expression of ATF family members (ATF1-ATF7) in …
Nitrate and Nitrite in the Diet: Protective and Harmful Effects in Health and Disease
Publication Year: 2025 Source: Curr Nutr Rep PMID: 40587020
PURPOSE OF REVIEW: The environmental presence of excess nitrogen poses a significant threat to biodiversity, human health, and climate stability. Conversely, nitrogen deficiency can hinder our ability to sustainably provide sufficient food for the global population. The impact of nitrates and nitrites on human health is intricately tied to their …
Need more literature?
The current database contains 98453 research articles. If you need to search for more literature or perform AI analysis, please use our knowledge acquisition module or explore external literature resources.
External Resources: Access comprehensive literature databases worldwide