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Calcium pyrophosphate deposition is associated with an increased risk for nephrolithiasis: A cohort study
Publication Year: 2025 Source: Semin Arthritis Rheum PMID: 39893939
BACKGROUND/OBJECTIVE: Calcium pyrophosphate deposition disease (CPPD) is a type of arthritis affecting aging adults that presents with chronic and acute inflammatory and non-inflammatory joint disease. While the etiology of CPPD is not fully understood, recent work suggests that it may be associated with other mineralization disorders. In this retrospective cohort …
Blood transcriptomics identifies FEZ1 as a potential biomarker for inflammatory bowel disease
Publication Year: 2025 Source: Comput Biol Med PMID: 39894009 DOI: 10.1016/j.compbiomed.2025.109742
INTRODUCTION: While the global burden of inflammatory bowel diseases (IBD) is increasing, the identification of novel therapeutic targets and biomarkers is of significant importance. In particular, blood transcriptomes provide a non-invasive source for biomarker discovery. Therefore, this study aimed to identify potential blood markers for IBD. METHODS: By employing an …
Review on Advances in Pediatric Endoscopy in the Management of Inflammatory Bowel Disease
Publication Year: 2025 Source: Curr Pediatr Rev PMID: 38265388 DOI: 10.2174/0115733963268547231128101929
Over the past decades, an increased importance has been given to gastrointestinal (GI) endoscopy in the management of children with inflammatory bowel diseases (IBD), considering that mucosal healing has been recognized as the optimal endpoint in the treat-to-target paradigm. The recent advances in technology and anesthesia have facilitated the comprehensive …
Infant Ustekinumab Clearance, Risk of Infection, and Development After Exposure During Pregnancy
Publication Year: 2025 Source: Clin Gastroenterol Hepatol PMID: 38278191
No Abstract
Food-derived peptides as novel therapeutic strategies for NLRP3 inflammasome-related diseases: a systematic review
Publication Year: 2025 Source: Crit Rev Food Sci Nutr PMID: 38153262
NLRP3 (NOD-, LRR- and pyrin domain-containing protein 3), a member of the nucleotide-binding domain (NOD) and leucine-rich repeat sequence (LRR) protein (NLR) family, plays an essential role in the inflammation initiation and inflammatory mediator secretion, and thus is also associated with many disease progressions. Food-derived bioactive peptides (FDBP) exhibit excellent …
Postoperative Hirschsprung's associated enterocolitis (HAEC): transition zone as putative histopathological predictive factor
Publication Year: 2025 Source: J Clin Pathol PMID: 38053256
No Abstract
Schaumann bodies deposited along myenteric plexus of the muscularis propria is a unique histopathological feature of Crohn's disease
Publication Year: 2025 Source: J Clin Pathol PMID: 38123350
AIMS: Schaumann bodies were first identified in sarcoidosis by Dr Schaumann in 1941. They were also detected in 10% of Crohn's disease (CD) cases in a study involving patients with surgically resected CD. However, the characteristics and significance of Schaumann bodies in CD have yet to be fully elucidated. This …
Mesalamine induced hepatotoxicity. Is mesalamine safe?
Publication Year: 2025 Source: Rev Esp Enferm Dig PMID: 38205716
Mesalamine is a medication used widely in the treatment of patients with inflammatory bowel disease. Although mesalamine is considered safe, hepatotoxicity has been reported with an incidence of 0-4%. We present the clinical picture of a patient with hepatotoxicity due to mesalamine. A 79-year-old woman in the context of chronic …
Physicochemical and biological stability of diluted vedolizumab in intravenous infusion bags
Publication Year: 2025 Source: Eur J Hosp Pharm PMID: 38212080
INTRODUCTION: Intravenous vedolizumab is a widely used monoclonal antibody for outpatients with inflammatory bowel disease. Drug preparation is performed on the day of administration, but is time consuming, causing unnecessary in-hospital patient delay and inefficient logistics for preparation and distribution. Storage of vedolizumab ready-to-administer infusions and distribution via pneumatic air …
Increasing Exposure to Inflammatory Bowel Diseases Education in Gastroenterology Fellowship: The Pilot IBD 101 Experience
Publication Year: 2025 Source: Inflamm Bowel Dis PMID: 38217539 DOI: 10.1093/ibd/izad311
BACKGROUND: Inflammatory bowel disease (IBD) management has become increasingly complex, and education varies across fellowship programs. IBD 101 was designed to introduce first-year gastroenterology (GI) fellows to IBD care and training. METHODS: In 2019, a cohort of fellows participated in a 1-day course with small group learning and group observed …
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