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Advancing oral immunology for improving oral health
Publication Year: 2025 Source: J Orofac Orthop PMID: 37314489
Although substantial progress has been made in dentistry in terms of diagnosis and therapy, current treatment methods in periodontology, orthodontics, endodontics, and oral and maxillofacial surgery, nevertheless, suffer from numerous limitations, some of which are associated with a dramatic reduction in the quality of life. Many general mechanisms of inflammation …
The gut-brain connection: Inflammatory bowel disease increases risk of acute ischemic stroke
Publication Year: 2025 Source: Interv Neuroradiol PMID: 37157802 DOI: 10.1177/15910199231170679
ObjectivesChronic inflammation of the gastrointestinal tract is a hallmark of inflammatory bowel disease (IBD). This increased inflammation is thought to induce a hypercoagulable state that increases the risk for stroke. However, few studies have examined the association between IBD and acute ischemic stroke (AIS). Thus, this study aims to investigate …
Efficacy and safety of mesenchymal stem cells in the treatment of perianal fistulas in Crohn's disease: a meta-analysis of randomized controlled trials
Publication Year: 2025 Source: Rev Esp Enferm Dig PMID: 36896932
OBJECTIVES: Local mesenchymal stem cell (MSC) therapy for perianal fistulas in Crohn's disease (CD) has yielded promising results, but it still remains controversial. In this study, we aimed to conduct a meta-analysis of randomized controlled trials (RCTs) to evaluate the efficacy and safety of MSC therapy for perianal CD (pCD). …
Morphological subtypes of colorectal low-grade intraepithelial neoplasia: diagnostic reproducibility, frequency and clinical impact
Publication Year: 2025 Source: J Clin Pathol PMID: 37985140 DOI: 10.1136/jcp-2023-209206
AIMS: Special histomorphological subtypes of colorectal low-grade intraepithelial neoplasia (LGIN) with variable prognostic impact were recently described in patients with inflammatory bowel disease (IBD) referred to as non-conventional dysplasia. However, they can also be found in patients without IBD. We aimed to analyse the reproducibility, frequency and prognostic impact of …
Diaphragm disease-When non-steroidal anti-inflammatory drugs bit the small bowel
Publication Year: 2025 Source: Indian J Gastroenterol PMID: 37855844
No Abstract
Research progress in the combined treatment of ulcerative colitis
Publication Year: 2025 Source: Rev Esp Enferm Dig PMID: 37073706
In recent years, more and more drugs have been used in the treatment of ulcerative colitis, but the efficacy of monotherapy is limited, especially for patients with refractory moderate to severe ulcerative colitis (UC). Combination therapy is mainly used for patients with a poor response or partial efficacy of monotherapy …
Stitch-induced caecal fecolith: An unusual long-term complication following laparoscopic appendicectomy
Publication Year: 2025 Source: J Minim Access Surg PMID: 37706403
A fecolith is a mass of accumulated hardened faecal matter usually seen in patients with Chagas disease, Hirschsprung's disease and inflammatory bowel disease. We report a 21-year-old female with chronic right lower abdominal pain post-appendicectomy. An abdominal computed tomography revealed a fecolith near the caecum and a right simple ovarian …
Enteropathic Arthritis
Publication Year: 2025 Source: StatPearls PMID: 37603630
Enteropathic arthritis refers to immune-driven rheumatologic conditions linked to gastrointestinal pathology, typically denoting the inflammatory spondyloarthropathies associated with inflammatory bowel disease (IBD) and reactive arthritis triggered by bacterial and parasitic infections. Psoriatic arthritis, ankylosing spondylitis, and undifferentiated spondyloarthropathy are other inflammatory spondyloarthropathies. Joint involvement is a common extraintestinal manifestation of …
Transfusion Selective IgA Deficiency
Publication Year: 2025 Source: StatPearls PMID: 33232010
Selective immunoglobulin A (IgA) deficiency is the most common immunodeficiency in individuals older than 4, after excluding other causes of hypogammaglobulinemia. Patients can be asymptomatic or experience recurrent infections and autoimmune illnesses. Recurrent infections, often caused by encapsulated bacteria such as Streptococcus pneumoniae and Haemophilus influenzae, most likely affect the …
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