Research Articles Library
Literature Analysis Tools
Advanced Search
Filter by PMID, year, source, DOI and other criteria
Literature Analysis
Analyze research trends and hotspots
Batch Export
Export search results to Excel/PDF
Fecal Incontinence
Publication Year: 2025 Source: StatPearls PMID: 29083703
Fecal incontinence is the involuntary passage of fecal matter through the anus or inability to control the discharge of bowel contents. This condition's severity can range from an involuntary passage of flatus to complete evacuation of fecal matter. Depending on the disease's severity, it significantly impacts a patient's quality of …
Ulcerative Colitis
Publication Year: 2025 Source: StatPearls PMID: 29083748
Ulcerative colitis is an idiopathic inflammatory condition of the colon that results in diffuse friability and superficial erosions on the colonic wall associated with bleeding. It is the most common form of inflammatory bowel disease worldwide. It characteristically involves inflammation restricted to the mucosa and submucosa of the colon. Typically, …
Crohn Disease
Publication Year: 2025 Source: StatPearls PMID: 28613792
Crohn disease is a form of inflammatory bowel disease (IBD) like ulcerative colitis, though Crohn disease often presents more subtly. Crohn disease is an immunologically mediated inflammatory gastrointestinal condition, with pathology involving the entire thickness of the bowel wall. The condition may involve any part of the gastrointestinal tract. Minnesota …
Estimated Glomerular Filtration Rate and the Risk of Inflammatory Bowel Disease in Adults: A Swedish Population-Based Study
Publication Year: 2024 Source: Inflamm Bowel Dis PMID: 36617285 DOI: 10.1093/ibd/izac267
BACKGROUND: Kidney complications are common in patients with long-standing inflammatory bowel disease (IBD). Whether kidney complications, defined as low estimated glomerular filtration rate (eGFR), may predispose to later IBD is unknown. METHODS: We analyzed the association between eGFR and the risk of being subsequently diagnosed with IBD among 1 612 …
Examination of a novel expression-based gene-SNP annotation strategy to identify tissue-specific contributions to heritability in multiple traits
Publication Year: 2024 Source: Eur J Hum Genet PMID: 36446896
Complex traits show clear patterns of tissue-specific expression influenced by single nucleotide polymorphisms (SNPs), yet current strategies aggregate SNP effects to genes by employing simple physical proximity-based windows. Here, we examined whether incorporating SNPs with effects on tissue-specific cis-expression would improve our ability to detect trait-relevant tissues across 31 complex …
5'AMP-activated protein kinase: an emerging target of phytochemicals to treat chronic inflammatory diseases
Publication Year: 2024 Source: Crit Rev Food Sci Nutr PMID: 36450301
Inflammation is a defensive response of the organism to traumatic, infectious, toxic, ischemic, and autoimmune injury. Inflammatory mediators are released to effectively eliminate the inflammatory trigger and restore homeostasis. However, failure of these processes can lead to chronic inflammatory conditions and diseases such as inflammatory bowel diseases, rheumatoid arthritis, inflammatory …
Quality of Surveillance Impacts the Colitis-Associated Advanced Neoplasia Risk: A Multicenter Case-Control Study
Publication Year: 2024 Source: Clin Gastroenterol Hepatol PMID: 36572110 DOI: 10.1016/j.cgh.2022.12.010
BACKGROUND AND AIMS: Although colorectal cancer (CRC) surveillance is embedded in clinical inflammatory bowel disease (IBD) practice, a subset of patients still develops advanced neoplasia (AN) (high-grade dysplasia [HGD] and/or CRC). We aimed to assess the impact of surveillance quality on AN risk in IBD. METHODS: In this multicenter case-control …
Effectiveness of Vitamin D Supplementation on Disease Course in Inflammatory Bowel Disease Patients: Systematic Review With Meta-Analysis
Publication Year: 2024 Source: Inflamm Bowel Dis PMID: 36579768 DOI: 10.1093/ibd/izac253
BACKGROUND: The vitamin D role in bone metabolism is well known; however, recent evidence suggests the impact of vitamin D in immune modulation and its implications in immune-mediated diseases, including inflammatory bowel disease (IBD). METHOD: We performed a systematic review with meta-analysis by a specific protocol (PROSPERO: CRD42022311184; March 2022, …
Iliac Branch Devices in the Repair of Ruptured Aorto-iliac Aneurysms: A Multicenter Study
Publication Year: 2024 Source: J Endovasc Ther PMID: 36683380 DOI: 10.1177/15266028221149922
PURPOSE: To evaluate the outcomes of preserving the internal iliac artery (IIA) with iliac branched devices (IBDs) during acute endovascular repair of ruptured aortoiliac aneurysms. MATERIAL AND METHODS: This is a multicenter retrospective review of all consecutive patients undergoing acute endovascular repair of ruptured aortoiliac aneurysm with an IBD at …
Need more literature?
The current database contains 98453 research articles. If you need to search for more literature or perform AI analysis, please use our knowledge acquisition module or explore external literature resources.
External Resources: Access comprehensive literature databases worldwide