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Long-Term Effectiveness and Safety of Proactive Therapeutic Drug Monitoring of Infliximab in Paediatric Inflammatory Bowel Disease: A Real-World Study
Publication Year: 2024 Source: Pharmaceutics PMID: 39771556 DOI: 10.3390/pharmaceutics16121577
BACKGROUND: This study evaluated the long-term effectiveness and safety of a multidisciplinary early proactive therapeutic drug monitoring (TDM) program combined with Bayesian forecasting for infliximab (IFX) dose adjustment in a real-world dataset of paediatric patients with inflammatory bowel disease (IBD). METHODS: A descriptive, ambispective, single-centre study of paediatric patients with …
Vedolizumab Clearance as a Surrogate Marker for Remission in Inflammatory Bowel Disease Patients: Insights from Real-World Pharmacokinetics
Publication Year: 2024 Source: Pharmaceutics PMID: 39771608 DOI: 10.3390/pharmaceutics16121629
Background/Objectives: Vedolizumab (VDZ) is approved in the treatment of patients with moderate to severe ulcerative colitis (UC) or Crohn's disease (CD). VDZ exhibits considerable variability in its pharmacokinetic (PK) profile, and its exposure-response relationship is not yet fully understood. The aim was to investigate the variability in VDZ trough levels …
Autoimmune pancreatitis as a risk factor of pancreatic cancer
Publication Year: 2024 Source: Klin Onkol PMID: 39772822
No Abstract
Progress in Prevention and Treatment of Dysplasia in Ulcerative Colitis Based on Cyclooxygenase-2/p53 Axis
Publication Year: 2024 Source: Zhongguo Yi Xue Ke Xue Yuan Xue Bao PMID: 39773513
No Abstract
Management of primary sclerosing cholangitis: Current state-of-the-art
Publication Year: 2024 Source: Hepatol Commun PMID: 39774274
No Abstract
Physical activity pattern and its influencing factors among patients with inflammatory bowel disease in East China
Publication Year: 2024 Source: BMJ Open PMID: 39806606 DOI: 10.1136/bmjopen-2024-088445
OBJECTIVE: To investigate the current level of physical activity (PA) and its influencing factors among patients with inflammatory bowel disease (IBD) in East China. DESIGN: Cross-sectional study. SETTING: Questionnaire survey recruiting from six tertiary referral hospitals in East China between October and December 2023. PARTICIPANTS: Patients with Crohn's disease (CD) …
Factors affecting perception and acceptance of colonoscopy in patients with inflammatory bowel disease
Publication Year: 2024 Source: Prev Med Rep PMID: 39807183 DOI: 10.1016/j.pmedr.2024.102951
OBJECTIVE: The noncompliance rate with routine or surveillance colonoscopies is high, and the underlying reasons remain unverified among Asian patients with inflammatory bowel disease (IBD). This study aimed to examine the perceptions of Asian patients with IBD regarding bowel preparation and colonoscopy and their attitudes toward the recommended intervals for …
Therapeutic efficacy of jeoryeong-tang in dextran sulfate sodium-induced mouse model of inflammatory bowel disease
Publication Year: 2024 Source: J Tradit Complement Med PMID: 39807272 DOI: 10.1016/j.jtcme.2024.11.018
BACKGROUND: Jeoryeong-tang (JRT) was first recorded in Shanghanlun. It is composed of Polyporus Sclerotium, Poria, Asini Corii Colla, Alisma Rhizome, and Talcum at the same weight ratio. These medicinal materials are known for diuretic and hemostatic effects and have been traditionally used to treat kidney and bladder diseases. However, their …
A pectic polysaccharide from Lycium ruthenicum Murray alleviates dextran sulfate sodium-induced colitis in mice
Publication Year: 2024 Source: Curr Res Food Sci PMID: 39807359 DOI: 10.1016/j.crfs.2024.100955
Inflammatory bowel disorders (IBD) can lead to severe complications like perforation, bleeding, and colon cancer, posing life-threatening risks. Lycium ruthenicum Murray (L. ruthenicum Murr.), rich in polysaccharides, has been utilized in traditional diets for thousands of years. This study explores the protective effects of the polysaccharide of L. ruthenicum on …
Ulcerative and Cytomegalovirus Colitis Associated with Fournier's Gangrene: A Case Report
Publication Year: 2024 Source: Middle East J Dig Dis PMID: 39807411 DOI: 10.34172/mejdd.2024.401
No Abstract
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