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The Role of Maternal and Early-Life Diet in Inflammatory Bowel Disease
Publication Year: 2024 Source: Nutrients PMID: 39770913 DOI: 10.3390/nu16244292
BACKGROUND/OBJECTIVES: Inflammatory bowel disease (IBD) is a chronic gastrointestinal disorder with debilitating symptoms and multifactorial etiology. Nutritional factors during adult life have been implicated in IBD pathogenesis. In addition, there is growing evidence that maternal and early-life diet may be associated with intestinal inflammation and colitis severity. The aim of …
Bovine Colostrum in Pediatric Nutrition and Health
Publication Year: 2024 Source: Nutrients PMID: 39770926 DOI: 10.3390/nu16244305
Bovine colostrum (BC), the first milk secreted by mammals after birth, is a trending alternative source for supplementing infants and children, offering benefits for gut and immune health. Its rich components, such as proteins, immunoglobulins, lactoferrin, and glycans, are used to fortify diets and support development. Preterm development is crucial, …
Small Intestinal Bacterial Overgrowth and Childhood Malnutrition: A Comprehensive Review of Available Evidence
Publication Year: 2024 Source: Nutrients PMID: 39770940
No Abstract
Diet and Microbiota Modulation for Chronic Pouchitis: Evidence, Challenges, and Opportunities
Publication Year: 2024 Source: Nutrients PMID: 39770958
No Abstract
Dietary Patterns and Fibre Intake Are Associated with Disease Activity in Australian Adults with Inflammatory Bowel Disease: An Exploratory Dietary Pattern Analysis
Publication Year: 2024 Source: Nutrients PMID: 39770970 DOI: 10.3390/nu16244349
BACKGROUND: Few studies have explored the relationship between habitual dietary patterns and disease activity in people with Inflammatory Bowel Disease (IBD). This cross-sectional study explored the association between dietary patterns and clinical and objective markers of inflammation in adults from the Australian IBD Microbiome Study. METHODS: Dietary patterns were derived …
Targeting the Calcium-Sensing Receptor in Chemically Induced Medium-Grade Colitis in Female BALB/C Mice
Publication Year: 2024 Source: Nutrients PMID: 39770982
No Abstract
Gut Microbiota and Metabolites Mediate Health Benefits of Oat and Oat Bran Consumption in IBD Mice
Publication Year: 2024 Source: Nutrients PMID: 39770986 DOI: 10.3390/nu16244365
BACKGROUND/OBJECTIVES: Inflammatory bowel disease (IBD) is a chronic condition influenced by a variety of factors, including genetics, the environment, and gut microbiota. The incidence of IBD is increasing globally. Previous studies have shown that interactions between diet and gut microbiota influence the pathogenesis and treatment of IBD. Proper dietary nutrition …
Importance of Fecal Microbiota Transplantation and Molecular Regulation as Therapeutic Strategies in Inflammatory Bowel Diseases
Publication Year: 2024 Source: Nutrients PMID: 39771031 DOI: 10.3390/nu16244411
Noncoding RNAs, particularly microRNAs (miRNAs) and small interfering RNAs (siRNAs), have emerged as key players in the pathogenesis and therapeutic strategies for inflammatory bowel disease (IBD). MiRNAs, small endogenous RNA molecules that silence target mRNAs to regulate gene expression, are closely linked to immune responses and inflammatory pathways in IBD. …
The Use of Tissue Concentrations of Biological and Small-Molecule Therapies in Clinical Studies of Inflammatory Bowel Diseases
Publication Year: 2024 Source: Pharmaceutics PMID: 39771479 DOI: 10.3390/pharmaceutics16121497
The introduction of biological therapies has revolutionized inflammatory bowel disease (IBD) management. A critical consideration in developing these therapies is ensuring adequate drug concentrations at the site of action. While blood-based biomarkers have shown limited utility in optimizing treatment (except for TNF-alpha inhibitors and thiopurines), tissue drug concentrations may offer …
Oral Delivery of miR146a Conjugated to Cerium Oxide Nanoparticles Improves an Established T Cell-Mediated Experimental Colitis in Mice
Publication Year: 2024 Source: Pharmaceutics PMID: 39771552
No Abstract
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