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Psoriasis and inflammatory bowel disease: concomitant IMID or paradoxical therapeutic effect? A scoping review on anti-IL-12/23 and anti-IL-23 antibodies
Publication Year: 2024 Source: Therap Adv Gastroenterol PMID: 39575159 DOI: 10.1177/17562848241299564
Inflammatory bowel diseases (IBD) and psoriasis are chronic inflammatory conditions belonging to the heterogeneous group of immune-mediated inflammatory diseases (IMIDs). A significant bidirectional link between these two entities has been observed, conditioning an increased risk of IBD in patients with psoriasis and vice-versa. Biological therapies used for IBD may lead …
MALAT1 promotes colonic epithelial cell apoptosis and pyroptosis by sponging miR-22-3p to enhance NLRP3 expression
Publication Year: 2024 Source: PeerJ PMID: 39575175
No Abstract
Fenofibrate as an Adjunct Therapy for Ulcerative Colitis: Targeting Inflammation via SIRT1, NLRP3, and AMPK Pathways: A Randomized Controlled Pilot Study
Publication Year: 2024 Source: Drug Des Devel Ther PMID: 39575188
No Abstract
Causal association between plasma metabolites and diverse autoimmune diseases: a two-sample bidirectional mendelian randomization study
Publication Year: 2024 Source: Front Immunol PMID: 39575250 DOI: 10.3389/fimmu.2024.1437688
BACKGROUND: Autoimmune diseases (ADs) are a category of conditions characterized by misrecognition of autologous tissues and organs by the immune system, leading to severe impairment of patients' health and quality of life. Increasing evidence suggests a connection between fluctuations in plasma metabolites and ADs. However, the existence of a causal …
STARD7 maintains intestinal epithelial mitochondria architecture, barrier integrity, and protection from colitis
Publication Year: 2024 Source: JCI Insight PMID: 39576011
No Abstract
Xanthohumol ameliorates dextran sodium sulfate-induced colitis in mice by inhibiting of NF-κB signaling pathways and modulating intestinal microbiota
Publication Year: 2024 Source: Eur J Nutr PMID: 39576384 DOI: 10.1007/s00394-024-03525-5
ETHNOPHARMACOLOGICAL RELEVANCE: Xanthohumol (XN), an isoprenylated flavonoid natural product found only in hops, possesses a variety of biological activities such as anticancer, anti-inflammatory, hepatoprotective, and anti-obesity. AIM OF THE STUDY: The aim of this study was to investigate the effects and mechanisms of XN on the treatment of colitis. MATERIALS …
In reviewing the emerging biomarkers of human inflammatory bowel disease (IBD): Endothelial progenitor cells (EPC) and their vesicles as potential biomarkers of cardiovascular manifestations and targets for personalized treatments
Publication Year: 2024 Source: Mech Ageing Dev PMID: 39577473 DOI: 10.1016/j.mad.2024.112006
Inflammatory bowel diseases (IBD) are chronic inflammatory and pathological conditions of the gastrointestinal tract, which include two main clinical subtypes: Crohn's disease (CD) and ulcerative colitis (UC). IBDs show an increase in their age-standardized global incidence rate worldwide, with no gender differences, although the age-standardized mortality rate has decreased over …
Effect of anthocyanins on metabolic syndrome through interacting with gut microbiota
Publication Year: 2024 Source: Pharmacol Res PMID: 39577753
No Abstract
A mitochondria-targeted nitric oxide probe with large Stokes shift for real-time imaging and evaluation of inflammatory bowel disease in situ
Publication Year: 2024 Source: Anal Chim Acta PMID: 39580178 DOI: 10.1016/j.aca.2024.343372
BACKGROUND: Inflammatory bowel disease (IBD) is a prevalent inflammatory disorder, and the abnormal expression of nitric oxide (NO) produced by biocatalysis of iNOS enzyme in mitochondria is directly associated with the occurrence and progression of IBD. Activatable fluorescent probes offer promising tools for early diagnosis of IBD, however, inadequate biodistribution …
Well-differentiated neuroendocrine tumor of the ileal pouch in a patient with ulcerative colitis and primary sclerosing cholangitis: report of a case and review of the literature
Publication Year: 2024 Source: Cesk Patol PMID: 39580234
No Abstract
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