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Identification of Specific microRNAs in Adipose Tissue Affected by Lipedema
Publication Year: 2024 Source: Curr Issues Mol Biol PMID: 39590304
No Abstract
Bright Luminal Sign on High b-Value Diffusion-Weighted Magnetic Resonance Enterography Imaging as a New Biomarker to Predict Fibrotic Strictures in Crohn's Disease Patients: A Retrospective Preliminary Study
Publication Year: 2024 Source: J Imaging PMID: 39590747
No Abstract
Harnessing a Safe Novel Lipid Nanoparticle: Targeted Oral Delivery to Colonic Epithelial and Macrophage Cells in a Colitis Mouse Model
Publication Year: 2024 Source: Nanomaterials (Basel) PMID: 39591041 DOI: 10.3390/nano14221800
A novel lipid nanoparticle (nLNP), formulated with three essential lipids to mimic ginger-derived exosomal particles, shows strong potential for delivering IL-22 mRNA specifically to the colon, presenting a unique oral drug delivery system for inflammatory bowel disease (IBD). However, its cellular targets and uptake behavior in healthy versus diseased colons …
STAR LIGHT Study: XBB.1.5 COVID-19 mRNA Vaccines Boost Systemic but Not Mucosal Immunity Against the SARS-CoV-2 JN.1 Variant in Patients with Chronic Liver Disease
Publication Year: 2024 Source: Vaccines (Basel) PMID: 39591144 DOI: 10.3390/vaccines12111241
BACKGROUND: Patients with chronic liver disease (CLD) have impaired vaccine immunogenicity and an excess risk of severe COVID-19. While variant-adapted COVID-19 mRNA vaccines are recommended for vulnerable individuals, their efficacy in patients with CLD has not been studied. METHODS: We present the first evaluation of XBB.1.5 COVID-19 vaccine immunogenicity against …
Beyond Suppression: Peripheral T Cell Responses to Vaccination in Inflammatory Bowel Disease Patients Undergoing Anti-Tumor-Necrosis-Factor Therapy
Publication Year: 2024 Source: Vaccines (Basel) PMID: 39591183 DOI: 10.3390/vaccines12111280
Alimentary tract inflammation in inflammatory bowel disease (IBD) is treated by systemically administered drugs that alter fundamental host immune responses. Biologics that target tumor necrosis factor (TNF) are first-line biologics in IBD, used widely for their effectiveness, steroid-sparing quality, and lower cost. While they enable a significant proportion of patients …
Milk-Derived Extracellular Vesicles: A Novel Perspective on Comparative Therapeutics and Targeted Nanocarrier Application
Publication Year: 2024 Source: Vaccines (Basel) PMID: 39591185
No Abstract
Impact of the uroperitoneum on the development of paralytic ileus: a preclinical study in the pig model
Publication Year: 2024 Source: World J Urol PMID: 39592512
No Abstract
Lactobacillus paracasei JY062 and its exopolysaccharide enhance the intestinal barrier through macrophage polarization and Th17/Treg cell balance
Publication Year: 2024 Source: Food Res Int PMID: 39593317
No Abstract
Clinical Comparison of OC-Sensor Pledia and Phadia 250 for Fecal Calprotectin Testing
Publication Year: 2024 Source: Diagnostics (Basel) PMID: 39594158 DOI: 10.3390/diagnostics14222490
Background: The fecal calprotectin (f-Cal) test is a convenient method used for differentiating inflammatory bowel disease (IBD) from functional bowel disorders. The OC-Sensor Pledia (OC-FCa; Eiken Chemical Co., Tokyo, Japan) is a latex agglutination turbidimetric immunoassay used for f-Cal measurements. We evaluated the clinical performance of OC-FCa and compared the …
Racial Disparities in Inpatient Hospital Outcomes of Primary Sclerosing Cholangitis in United States: Nationwide Analysis
Publication Year: 2024 Source: Diagnostics (Basel) PMID: 39594159
No Abstract
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