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The Effect of Biologic Agents on Steatotic Liver Disease in Patients with Inflammatory Bowel Disease: A Prospective, Open-Label Comparative Trial

Publication Year: 2024 Source: Pharmaceuticals (Basel) PMID: 39598344 DOI: 10.3390/ph17111432

BACKGROUND: Biologic agents used in patients with inflammatory bowel diseases (IBD) may influence the pathophysiology of coexistent metabolic-dysfunction associated steatotic liver disease (MASLD). This study primarily aimed to evaluate the six-month effect of infliximab or vedolizumab vs. no biologics on presumed hepatic steatosis in patients with IBD. Secondary endpoints were …

Optimizing Treatment Outcomes in Crohn's Disease: A Comprehensive Systematic Review and Meta-Analysis of Regenerative Therapies with Emphasis on Platelet-Rich Plasma

Publication Year: 2024 Source: Pharmaceuticals (Basel) PMID: 39598430

No Abstract

Treatment of Inflammatory Bowel Disease by Using Curcumin-Containing Self-Microemulsifying Delivery System: Macroscopic and Microscopic Analysis

Publication Year: 2024 Source: Pharmaceutics PMID: 39598530 DOI: 10.3390/pharmaceutics16111406

Background: The lack of local availability for drugs in the colon can be addressed by preparing a self-microemulsifying drug delivery system (SMEDDS) of curcumin (Cur) which is ultimately used for the treatment of inflammatory bowel disease (IBD). Methods: From preformulation studies, Lauroglycol FCC (oil), Tween 80 (surfactant), Transcutol HP (co-surfactant), …

Drug Interaction-Informed Approaches to Inflammatory Bowel Disease Management

Publication Year: 2024 Source: Pharmaceutics PMID: 39598554 DOI: 10.3390/pharmaceutics16111431

Inflammatory bowel disease (IBD) is a complex and chronic condition that requires the use of various pharmacological agents for its management. Despite advancements in IBD research, the multifaceted mechanisms involved continue to pose significant challenges for strategic prevention. Therefore, it is crucial to prioritize safe and effective treatment strategies using …

Adjunct Therapies to Standard Care for IBS and IBD Patients: Digestive Symptoms Improvement and Quality of Life Optimization

Publication Year: 2024 Source: Nutrients PMID: 39599713 DOI: 10.3390/nu16223927

Background: The prevalence of both inflammatory bowel diseases (IBD) and Irritable Bowel Syndrome (IBS) is increasing, with persistent digestive symptoms, an altered quality of life, and higher rates of anxiety, chronic fatigue, and sleep trouble than the general population. Methods: This scoping review will analyze the latest clinical practice recommendations …

Effect of Intermittent Fasting on Immune Parameters and Intestinal Inflammation

Publication Year: 2024 Source: Nutrients PMID: 39599741 DOI: 10.3390/nu16223956

No Abstract

Health Benefits of Prebiotics, Probiotics, Synbiotics, and Postbiotics

Publication Year: 2024 Source: Nutrients PMID: 39599742 DOI: 10.3390/nu16223955

The trillions of microbes that constitute the human gut microbiome play a crucial role in digestive health, immune response regulation, and psychological wellness. Maintaining gut microbiota is essential as metabolic diseases are associated with it. Functional food ingredients potentially improving gut health include prebiotics, probiotics, synbiotics, and postbiotics (PPSPs). While …

Raising the bar in ulcerative colitis management

Publication Year: 2024 Source: Therap Adv Gastroenterol PMID: 39600566

No Abstract

Epstein-Barr Virus-Positive Diffuse Large B-cell Lymphoma Arising in Ulcerative Colitis: An Instructive Case Report and Literature Review

Publication Year: 2024 Source: Cureus PMID: 39600784

No Abstract

Contrast agents for MR enterography

Publication Year: 2024 Source: Radiologia (Engl Ed) PMID: 39603744

No Abstract

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