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Investigating resilience in patients with IBD: preliminary insights for understanding disease-specific resilience skills

Publication Year: 2024 Source: Front Psychol PMID: 39606191 DOI: 10.3389/fpsyg.2024.1486401

INTRODUCTION: Inflammatory bowel diseases (IBDs) significantly impact patients' quality of life. While research highlights the potential role of psychological resilience to enhance overall health and well-being in patients with chronic conditions, its specific role in the context of IBD remains underexplored. This study aimed to identify key components of resilience, …

Improving Differentiation of Crohn's Disease and Ulcerative Colitis Proteomes through Protein-Wide Association Study Feature Selection in Machine Learning

Publication Year: 2024 Source: medRxiv PMID: 39606394 DOI: 10.1101/2024.11.13.24316854

BACKGROUND AND AIMS: Diagnostic differentiation between Crohn's disease (CD) and ulcerative colitis (UC) is crucial for timely and suitable therapeutic measures. The current gold standard for differentiating between CD and UC involves endoscopy and histology, which are invasive and costly. We aimed to identify blood plasma proteomic signatures using a …

Cell-derived biomimetic drug delivery system for inflammatory bowel disease therapy

Publication Year: 2024 Source: Mater Today Bio PMID: 39606424 DOI: 10.1016/j.mtbio.2024.101332

Inflammatory bowel disease (IBD) is a chronic recurrent disease with an increasing incidence year by year. At present, no safe and effective treatment for IBD exists. Thus, there is an urgent need to create new therapeutic options that have decreased adverse effects and positive clinical efficacy. A range of nanomaterials …

Diagnostic and Therapeutic Microbial Circuit with Application to Intestinal Inflammation

Publication Year: 2024 Source: ACS Synth Biol PMID: 39607341

No Abstract

The probiotic Lactobacillus plantarum alleviates colitis by modulating gut microflora to activate PPARγ and inhibit MAPKs/NF-κB

Publication Year: 2024 Source: Eur J Nutr PMID: 39607600

No Abstract

Undetected Dysplasia at Colectomy in Patients With Inflammatory Bowel Diseases. What Are We Missing?

Publication Year: 2024 Source: Inflamm Bowel Dis PMID: 39607850 DOI: 10.1093/ibd/izae274

BACKGROUND AND AIMS: Patients with inflammatory bowel disease (IBD) have a higher risk of developing colorectal dysplasia and colorectal cancer compared to the general population. Although the use of surveillance protocols has improved the ability to detect dysplasia, some lesions are still missed at colonoscopy. This study aims to determine …

Prophylactic saline-immersion snare-tip vessel coagulation after colorectal endoscopic resection

Publication Year: 2024 Source: Endoscopy PMID: 39608354 DOI: 10.1055/a-2419-2195

No Abstract

Autologous faecal microbiota transplantation via double barrel stoma to treat chronic diversion colitis

Publication Year: 2024 Source: BMJ Case Rep PMID: 39608831

No Abstract

Rewiring Tryptophan Metabolism via Programmable Probiotic Integrated by Dual-Layered Microcapsule Protects against Inflammatory Bowel Disease in Mice

Publication Year: 2024 Source: ACS Nano PMID: 39609102 DOI: 10.1021/acsnano.4c12801

Intestinal dysbiosis and the associated l-tryptophan metabolic disorder are pivotal in inflammatory bowel disease progression, leading to a compromised intestinal barrier integrity. Remedying the dysfunction in tryptophan metabolism has emerged as a promising therapeutic strategy. Herein, we reprogram the tryptophan metabolism in situ by EcN-TRP@A/G, encapsulating the engineered probiotic, EcN-TRP, …

Bacteroides thetaiotaomicron enhances H(2)S production in Bilophila wadsworthia

Publication Year: 2024 Source: Gut Microbes PMID: 39609271

No Abstract

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