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Comparing Point-of-Care Technology to ELISA Testing for Infliximab and Adalimumab Levels in Adult Inflammatory Bowel Disease Patients: A Prospective Pilot Study
Publication Year: 2024 Source: Diagnostics (Basel) PMID: 39410544 DOI: 10.3390/diagnostics14192140
Introduction: Therapeutic drug monitoring (TDM) has proven to be a valuable strategy for optimizing biologic therapies, among which are anti-tumor necrosis factor (anti-TNF) treatments in inflammatory bowel disease (IBD). In particular, reactive TDM has been shown to manage treatment failures more cost-effectively than empirical dose adjustments for anti-TNF drugs. However, …
Inflammation-Responsive Polyion Complex Vesicles for Autoimmune Disease Therapy via Cell-Free DNA Scavenging and Inflammatory Microenvironment Modulation
Publication Year: 2024 Source: ACS Nano PMID: 39410737
No Abstract
The Impact of Hormone Therapy on Inflammatory Bowel Disease in Transgender and Nonbinary Individuals
Publication Year: 2024 Source: Inflamm Bowel Dis PMID: 39410842 DOI: 10.1093/ibd/izae236
BACKGROUND: Inflammatory bowel disease (IBD) is a global healthcare problem that affects around 3 million people in the United States. Although the impact of gender-affirming hormone therapy (GAHT) on IBD severity has been studied in cisgender patients, there is currently no literature on the impact of exogenous hormone therapy (HT) …
Long-term outcomes and quality of life in patients with Hirschsprung disease
Publication Year: 2024 Source: World J Pediatr Surg PMID: 39410940
No Abstract
Corrigendum: Therapeutic role of extracellular vesicles from human umbilical cord mesenchymal stem cells and their wide therapeutic implications in inflammatory bowel disease and other inflammatory disorder
Publication Year: 2024 Source: Front Med (Lausanne) PMID: 39411192
No Abstract
Comprehensive data optimization and risk prediction framework: machine learning methods for inflammatory bowel disease prediction based on the human gut microbiome data
Publication Year: 2024 Source: Front Microbiol PMID: 39411443 DOI: 10.3389/fmicb.2024.1483084
Over the past decade, the prevalence of inflammatory bowel disease (IBD) has significantly increased, making early detection crucial for improving patient survival rates. Medical research suggests that changes in the human gut microbiome are closely linked to IBD onset, playing a critical role in its prediction. However, the current gut …
Primary Sclerosing Cholangitis and Crohn's Disease: A Rare Association
Publication Year: 2024 Source: Cureus PMID: 39411594 DOI: 10.7759/cureus.69397
Inflammatory bowel disease (IBD) and primary sclerosing cholangitis (PSC) are closely associated disease entities that, when present in combination, create a phenotypically different summative disease referred to as PSC-IBD. The hallmark of Crohn's disease is persistent inflammation that can affect any part of the gastrointestinal system, from the mouth to …
Rhombencephalitis With Long Segment Transverse Myelitis: A Presentation With a Rare Etiology
Publication Year: 2024 Source: Cureus PMID: 39411647
No Abstract
New onset inflammatory bowel disease after initiation of anti-IL-17a treatment: a case series
Publication Year: 2024 Source: Acta Gastroenterol Belg PMID: 39411795 DOI: 10.51821/87.3.12874
Immune mediated inflammatory diseases (IMIDs) are a heterogenous group of inflammatory disorders of joint, skin, and gut characterized by both shared and distinct pathological pathways. This complexity has therapeutic implications, as not all IMIDs exhibit responsiveness to available biologicals. Moreover, cases have been documented where patients undergoing biologic therapy experience …
Durable Immune Response and Long-term Efficacy of COVID-19 Vaccination in Children With Inflammatory Bowel Disease
Publication Year: 2024 Source: Inflamm Bowel Dis PMID: 39412147 DOI: 10.1093/ibd/izae225
BACKGROUND: Children with inflammatory bowel disease (IBD) may have diminished serologic response to severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) vaccination and increased risk for subsequent severe coronavirus disease 2019 (COVID-19) infection. We sought to describe outcomes among those who developed SARS-CoV-2 infection following vaccination, characterize SARS-CoV-2 antibodies 1 year …
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