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Long-Term Effectiveness and Safety of Ustekinumab in Crohn's Disease: Results from a Large Real-Life Cohort Study
Publication Year: 2024 Source: J Clin Med PMID: 39685651
No Abstract
Associations Between Polymorphisms of Genes Related to Vitamin D Pathway and the Response to Vedolizumab and Ustekinumab in Inflammatory Bowel Disease
Publication Year: 2024 Source: J Clin Med PMID: 39685734 DOI: 10.3390/jcm13237277
Background/Objectives: Vitamin D (VD) has immunoregulatory properties, generating interest in its potential to influence therapeutic outcomes in inflammatory bowel disease (IBD), other than affecting the expression of genes encoding enzymes and transporters involved in drug metabolism and transport. This study investigated VD-related single nucleotide polymorphisms (SNPs) as predictors of clinical …
Recent Advances in the Management of Acute Severe Ulcerative Colitis
Publication Year: 2024 Source: J Clin Med PMID: 39685904
No Abstract
Efficacy of different dietary therapy strategies in active pediatric Crohn's disease: a systematic review and network meta-analysis
Publication Year: 2024 Source: PeerJ PMID: 39686992
No Abstract
Alterations of fractional anisotropy and white matter integrity in irritable bowel syndrome: a systematic review and meta-analysis of diffusion tensor imaging studies
Publication Year: 2024 Source: Front Neurosci PMID: 39687489 DOI: 10.3389/fnins.2024.1426218
BACKGROUND AND AIM: The neurological processes responsible for irritable bowel syndrome (IBS) pathophysiology and its clinical potentials are not fully understood. The current study aimed to examine white matter microstructural abnormalities and the reasons behind white matter impairment in individuals with irritable bowel syndrome by performing a meta-analysis of diffusion …
Therapeutic potential of Parabacteroides distasonis in gastrointestinal and hepatic disease
Publication Year: 2024 Source: MedComm (2020) PMID: 39687780
No Abstract
Characteristics of the gut microbiota and the effect of Bifidobacterium in very early-onset inflammatory bowel disease patients with IL10RA mutations
Publication Year: 2024 Source: Front Microbiol PMID: 39687875 DOI: 10.3389/fmicb.2024.1479779
Very early-onset inflammatory bowel disease (VEO-IBD) is a distinct subtype of inflammatory bowel disease (IBD) characterized by onset before the age of 6 years, and patients often exhibit more severe clinical features. Interleukin 10 receptor alpha (IL10RA) is a hotspot mutation in the Chinese population and is associated with a …
Advancements in the management of pediatric inflammatory bowel disease
Publication Year: 2024 Source: Expert Rev Gastroenterol Hepatol PMID: 39688852 DOI: 10.1080/17474124.2024.2444555
INTRODUCTION: The management of pediatric inflammatory bowel disease (PIBD) has drastically changed in the last decade. The limited availability of new biologics or small molecule therapies, and concerns about durability in children has necessitated the development of other advances in management to optimize care. AREAS COVERED: This review covers guidance …
NEDD4L mediates intestinal epithelial cell ferroptosis to restrict inflammatory bowel diseases and colorectal tumorigenesis
Publication Year: 2024 Source: J Clin Invest PMID: 39688910
No Abstract
Bile acid-induced metabolic changes in the colon promote Enterobacteriaceae expansion and associate with dysbiosis in Crohn's disease
Publication Year: 2024 Source: Sci Signal PMID: 39689182 DOI: 10.1126/scisignal.adl1786
Bile acids (BAs) affect the growth of potentially pathogenic commensals, including those from the Enterobacteriaceae family, which are frequently overrepresented in inflammatory bowel disease (IBD). BAs are normally reabsorbed in the ileum for recycling and are often increased in the colonic lumina of patients with IBD, including those with Crohn's …
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