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Identification of complex Plasmodium falciparum genetic backgrounds circulating in Africa: a multicountry genomic epidemiology analysis

Publication Year: 2024 Source: Lancet Microbe PMID: 39522520 DOI: 10.1016/j.lanmic.2024.07.004

BACKGROUND: The population structure of the malaria parasite Plasmodium falciparum can reveal underlying adaptive evolutionary processes. Selective pressures to maintain complex genetic backgrounds can encourage inbreeding, producing distinct parasite clusters identifiable by population structure analyses. METHODS: We analysed population structure in 3783 P falciparum genomes from 21 countries across Africa, …

Food additives and their implication in inflammatory bowel disease and metabolic syndrome

Publication Year: 2024 Source: Clin Nutr ESPEN PMID: 39522876 DOI: 10.1016/j.clnesp.2024.10.171

Over the past half a century the Western diet (WD) has become saturated with food additives. During the same time, there has been an increase in Western diseases, such as inflammatory bowel disease (IBD) and metabolic syndrome (MetS). Emerging research has shown that food additives may be implicated in these …

Poria cocos polysaccharide alleviates dextran sulphate sodium-induced ulcerative colitis in mice by modulating intestinal inflammatory responses and microbial dysbiosis

Publication Year: 2024 Source: Int J Biol Macromol PMID: 39522895

No Abstract

[The history and future perspective of the management for neoplasia with inflammatory bowel disease]

Publication Year: 2024 Source: Nihon Shokakibyo Gakkai Zasshi PMID: 39522963

No Abstract

[Developmental mechanism of inflammatory bowel disease-associated cancer]

Publication Year: 2024 Source: Nihon Shokakibyo Gakkai Zasshi PMID: 39522964

No Abstract

[Pathological features of IBD-associated neoplasia]

Publication Year: 2024 Source: Nihon Shokakibyo Gakkai Zasshi PMID: 39522965 DOI: 10.11405/nisshoshi.121.875

No Abstract

[Tumor management related to Crohn's disease]

Publication Year: 2024 Source: Nihon Shokakibyo Gakkai Zasshi PMID: 39522967

No Abstract

Exploring the mechanisms of chronic obstructive pulmonary disease and Crohn's disease: a bioinformatics-based study

Publication Year: 2024 Source: Sci Rep PMID: 39523420

No Abstract

Daikenchuto, a Japanese herbal medicine, ameliorates experimental colitis in a murine model by inducing secretory leukocyte protease inhibitor and modulating the gut microbiota

Publication Year: 2024 Source: Front Immunol PMID: 39524440 DOI: 10.3389/fimmu.2024.1457562

BACKGROUND: Inflammatory bowel disease (IBD) is a refractory inflammatory disorder of the intestine, which is probably triggered by dysfunction of the intestinal epithelial barrier. Secretory leukocyte protease inhibitor (SLPI) secreted by colon epithelial cells protects against intestinal inflammation by exerting anti-protease and anti-microbial activities. Daikenchuto (DKT) is one of the …

Goblet cells: guardians of gut immunity and their role in gastrointestinal diseases

Publication Year: 2024 Source: eGastroenterology PMID: 39524932

No Abstract

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