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Small bowel ulcers and hypoproteinemia, differential diagnosis beyond inflamatory bowel disease

Publication Year: 2024 Source: Rev Esp Enferm Dig PMID: 39530556 DOI: 10.17235/reed.2024.10859/2024

Protein-losing enteropathy is a relatively uncommon syndrome characterized by excessive loss of proteins into the intestinal lumen. It can be caused by various etiologies. Inflammatory bowel disease (IBD) is the first condition we think of when we meet a patient with intestinal ulcers and hypoproteinemia. However, there are many other …

Clinical-histological correlation of various symptoms in the diagnosis of pediatric Crohn's disease

Publication Year: 2024 Source: Rev Esp Enferm Dig PMID: 39530559 DOI: 10.17235/reed.2024.10861/2024

Crohn's disease (CD) is a relapsing-remitting inflammatory bowel disease (IBD) affecting the gastrointestinal tract. Its symptoms are nonspecific, with weight loss, diarrhea, and abdominal pain being classic, though their diagnostic utility is controversial (2). We evaluated the clinical-pathological association of different symptoms in CD through an analytical study of patients …

Broadening perspectives in the treatment of chronic pouchitis

Publication Year: 2024 Source: Rev Esp Enferm Dig PMID: 39530569

No Abstract

Looking Inside of the Intestinal Permeability Regulation by Protein-Derivatives from Bovine Milk

Publication Year: 2024 Source: Mol Nutr Food Res PMID: 39530631 DOI: 10.1002/mnfr.202400384

The prime function of the epithelium is to regulate the intestinal permeability; the latter is a quantitative parameter that refers to the measurement of the rate of passage of solutes through the epithelial monolayer. Function of epithelial monolayer depends on the expression of protein complexes known as tight junction proteins; …

Patient perception of bowel urgency and remission in moderately to severely active Crohn's disease or ulcerative colitis: a qualitative study

Publication Year: 2024 Source: J Patient Rep Outcomes PMID: 39531103

No Abstract

Budget impact analysis of subcutaneous infliximab (CT-P13 SC) for treating inflammatory bowel disease in Saudi Arabia: Analysis from payer perspective

Publication Year: 2024 Source: PLoS One PMID: 39531466 DOI: 10.1371/journal.pone.0312603

BACKGROUND: The Saudi Food and Drug Authority (SFDA) has approved the subcutaneous (SC) administration of infliximab, presenting a more convenient alternative with reduced outpatient visits and diminished expenses compared to the intravenous (IV) administration. However, the financial implications of this formulation have not been examined from the perspective of Saudi …

Low Rates of Short-Term Anastomotic Complications After Kono-S versus Side-to-Side Stapled Anastomosis

Publication Year: 2024 Source: J Surg Res PMID: 39531983

No Abstract

The efficacy of CT-P13, a biosimilar of infliximab, in inflammatory bowel diseases: a systematic review and meta-analysis

Publication Year: 2024 Source: BMC Gastroenterol PMID: 39533176 DOI: 10.1186/s12876-024-03480-9

BACKGROUND: Since 2015, an infliximab biosimilar, CT-P13, has been approved for commercial use in many countries, easing the economic burden borne by society and patients. Many clinical trials investigating CT-P13 for the treatment of IBD have been conducted and reported that it may be a substitute for infliximab. However, the …

Comprehensive analysis of psychological symptoms and quality of life in early patients with IBD: a multicenter study from China

Publication Year: 2024 Source: BMC Psychiatry PMID: 39533191 DOI: 10.1186/s12888-024-06247-4

OBJECTIVE: To investigate the prevalence and risk factors of psychological symptoms and quality of life (QoL) in early patients with inflammatory bowel disease (IBD). METHODS: From September 2021 to May 2022, a unified questionnaire was developed to collect clinical data from early patients with IBD from 42 tertiary care hospitals. …

7-hydroxycoumarin ameliorates ulcerative colitis in mice by inhibiting the MAPK pathway and alleviating gut microbiota dysbiosis

Publication Year: 2024 Source: BMC Gastroenterol PMID: 39533196

No Abstract

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