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Inflammatory bowel disease and risk of ophthalmic inflammation-related diseases: a two-sample Mendelian randomization study
Publication Year: 2024 Source: Int J Ophthalmol PMID: 39559299 DOI: 10.18240/ijo.2024.11.17
AIM: To investigate the causal effect of inflammatory bowel disease (IBD) on ocular inflammation using Mendelian randomization (MR) analysis. METHODS: Genetic instruments associated with inflammatory bowel disease (IBD), ulcerative colitis (UC), and Crohn's disease (CD) were derived from the largest genome-wide association studies (GWAS) published to date. The FinnGen research …
Gain-of-Function Variant in Spleen Tyrosine Kinase Regulates Macrophage Migration and Functions to Promote Intestinal Inflammation
Publication Year: 2024 Source: J Inflamm Res PMID: 39559401
No Abstract
Panduratin A mitigates inflammation and oxidative stress in DSS-induced colitis mice model
Publication Year: 2024 Source: Future Sci OA PMID: 39559852
No Abstract
Expanding Support Beyond Clinical Care in IBD Patients
Publication Year: 2024 Source: United European Gastroenterol J PMID: 39560459 DOI: 10.1002/ueg2.12715
INTRODUCTION: A rational discussion of the impact of Pain, Fatigue and Bowel Incontinence on the Quality of Life of People Living With Inflammatory Bowel Disease: A UK Cross- Sectional Survey. CONCLUSION: To help Inflammatory Bowel Disease patients manage symptoms and improve quality of life by incorporating a multifaceted community health …
A bidirectional Mendelian randomization study of spleen volume and Crohn disease
Publication Year: 2024 Source: Medicine (Baltimore) PMID: 39560526
No Abstract
The application of sphingomyelin in mediating the causal role of the T-cell surface glycoprotein CD5 in Crohn's disease: A two-step Mendelian randomization study
Publication Year: 2024 Source: Medicine (Baltimore) PMID: 39560554
No Abstract
Immunomolecular and reactivity landscapes of gut IgA subclasses in homeostasis and inflammatory bowel disease
Publication Year: 2024 Source: J Exp Med PMID: 39560666 DOI: 10.1084/jem.20230079
The human gut includes plasma cells (PCs) expressing immunoglobulin A1 (IgA1) or IgA2, two structurally distinct IgA subclasses with elusive regulation, function, and reactivity. We show here that intestinal IgA1+ and IgA2+ PCs co-emerged early in life, comparably accumulated somatic mutations, and were enriched within short-lived CD19+ and long-lived CD19- …
Quantified small bowel motility assessment on magnetic resonance enterography in paediatric inflammatory bowel disease - does it reflect clinical response?
Publication Year: 2024 Source: Pediatr Radiol PMID: 39560731
No Abstract
Unraveling the molecular mechanism of aqueous extract of Sargentodoxa cuneata against ulcerative colitis from serum metabolomics and bioinformatics perspectives
Publication Year: 2024 Source: J Chromatogr B Analyt Technol Biomed Life Sci PMID: 39561468
No Abstract
Ultrasound of the Foot and Ankle in Peripheral Spondyloarthritis
Publication Year: 2024 Source: Semin Musculoskelet Radiol PMID: 39561755
No Abstract
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