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The resolvin D2 and omega-3 polyunsaturated fatty acid as a new possible therapeutic approach for inflammatory bowel diseases
Publication Year: 2024 Source: Sci Rep PMID: 39562789 DOI: 10.1038/s41598-024-80051-8
Inflammatory bowel diseases (IBD) are idiopathic disorders characterized by chronic gastrointestinal inflammation. Given conventional therapies' adverse effects and clinical failures, novel approaches are being investigated. Recent studies have highlighted the role of specialized pro-resolving lipid mediators (SPMs) in the active resolution of chronic inflammation. In this regard, omega-3 fatty acid-derived …
Gastrointestinal Tuberculosis: 8-year Experience from a Tertiary Care Hospital in North India
Publication Year: 2024 Source: J Assoc Physicians India PMID: 39563119
No Abstract
Trends in medications for autoimmune disorders during pregnancy and factors for their discontinuation: a population-based study
Publication Year: 2024 Source: BMC Pregnancy Childbirth PMID: 39563243
No Abstract
Micro-DeMix: a mixture beta-multinomial model for investigating the heterogeneity of the stool microbiome compositions
Publication Year: 2024 Source: Bioinformatics PMID: 39563467
No Abstract
Real-World Effectiveness and Safety of Carotegrast Methyl in Japanese Patients with Moderately Active Ulcerative Colitis
Publication Year: 2024 Source: Inflamm Intest Dis PMID: 39563683
No Abstract
Impact of Concomitant Prescriptions and Lifestyle Factors on the Initial Course of Newly Diagnosed Inflammatory Bowel Disease
Publication Year: 2024 Source: Inflamm Intest Dis PMID: 39563684 DOI: 10.1159/000541984
INTRODUCTION: There is a close relationship between the relapse of inflammatory bowel disease (IBD) and lifestyle factors, including concomitant medications such as nonsteroidal anti-inflammatory drugs (NSAIDs), antithrombotic drugs, smoking status, and alcohol consumption. However, solid evidence is limited regarding the risk factors at diagnosis and initial disease course. This study …
Expression of IL-7Rα(low)CX3CR1(+) CD8(+) T Cells and α4β7 Integrin Tagged T Cells Related to Mucosal Immunity in Children with Inflammatory Bowel Disease
Publication Year: 2024 Source: Pediatr Gastroenterol Hepatol Nutr PMID: 39563840 DOI: 10.5223/pghn.2024.27.6.345
PURPOSE: The study aimed to investigate the recruiting of T lymphocytes including IL-7Ralpha(low) CX3CR1(+) effector memory (EM) CD8(+) T cells and alpha4beta7 integrin tagged T cells to inflamed intestinal mucosa. METHODS: Whole blood and mucosal tissues of intestine were collected from 40 children with or without inflammatory bowel disease (IBD). …
The Value of Colonoscopy in Assessing Rectal Bleeding in Patients Referred From Outpatient Care Units in Erbil, Iraq
Publication Year: 2024 Source: Cureus PMID: 39564041
No Abstract
Vagal stimulation ameliorates murine colitis by regulating SUMOylation
Publication Year: 2024 Source: Sci Transl Med PMID: 39565873 DOI: 10.1126/scitranslmed.adl2184
Inflammatory bowel diseases (IBDs) are chronic debilitating conditions without cure, the etiologies of which are unknown, that shorten the lifespans of 7 million patients worldwide by nearly 10%. Here, we found that decreased autonomic parasympathetic tone resulted in increased IBD susceptibility and mortality in mouse models of disease. Conversely, vagal …
Involvement of Mediterranean fever gene mutations in colchicine-responsive enterocolitis: a retrospective cohort study
Publication Year: 2024 Source: EBioMedicine PMID: 39566399
No Abstract
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