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Development of a novel complex inflammatory bowel disease mouse model: Reproducing human inflammatory bowel disease etiologies in mice
Publication Year: 2024 Source: PLoS One PMID: 39570897 DOI: 10.1371/journal.pone.0311310
Inflammatory bowel disease (IBD), caused by environmental factors associated with the host's genetic traits, is represented by Crohn's disease and ulcerative colitis. Despite the increasing number of patients with IBD, the current treatment is limited to symptomatic therapy. A complex IBD model mimicking the human IBD etiology is required to …
Bulk T cell repertoire sequencing (TCR-Seq) is a powerful technology for understanding inflammation-mediated diseases
Publication Year: 2024 Source: J Autoimmun PMID: 39571301
No Abstract
Gender Inequity in Pharma-Supported Inflammatory Bowel Disease Presentations: Shining a Light on Opportunities for Equality and Transparency in Medical Research
Publication Year: 2024 Source: Gastroenterology PMID: 39572131
No Abstract
AGA Living Clinical Practice Guideline on Pharmacological Management of Moderate-to-Severe Ulcerative Colitis
Publication Year: 2024 Source: Gastroenterology PMID: 39572132
No Abstract
Phenolics-Rich Extract from Agarwood Leaf-Tea Alleviate Dextran Sulfate Sodium (DSS)-Induced Ulcerative Colitis Via Modulating Intestinal Barrier Function, Liver Inflammation, and Gut Microbiota
Publication Year: 2024 Source: Mol Nutr Food Res PMID: 39573890
No Abstract
A novel computational approach for the mining of signature pathways using species co-occurrence networks in gut microbiomes
Publication Year: 2024 Source: BMC Microbiol PMID: 39574009 DOI: 10.1186/s12866-024-03633-6
BACKGROUND: Advances in metagenome sequencing data continue to enable new methods for analyzing biological systems. When handling microbial profile data, metagenome sequencing has proven to be far more comprehensive than traditional methods such as 16s rRNA data, which rely on partial sequences. Microbial community profiling can be used to obtain …
Proactive therapeutic drug monitoring of biologic drugs in patients with inflammatory bowel disease, inflammatory arthritis, and psoriasis: systematic review and meta-analysis
Publication Year: 2024 Source: BMJ Med PMID: 39574425
No Abstract
Probiotic Potential in Irritable Bowel Syndrome and Inflammatory Bowel Disease: A Comprehensive Systematic Review
Publication Year: 2024 Source: Cureus PMID: 39575029 DOI: 10.7759/cureus.72089
Irritable bowel syndrome (IBS) and inflammatory bowel disease (IBD) are prevalent gastrointestinal disorders with significant global prevalence. Conventional treatments often have adverse effects, prompting interest in probiotics as alternative therapies. This systematic review assesses the efficacy of probiotics in managing symptoms and improving outcomes in adult patients with IBS and …
Abdominal Pain in Inflammatory Bowel Disease-Epidemiology, Pathophysiology, and Management: A Narrative Review
Publication Year: 2024 Source: Pain Ther PMID: 39466554 DOI: 10.1007/s40122-024-00672-9
Abdominal pain is a major symptom of inflammatory bowel disease (IBD), including Crohn's disease and ulcerative colitis, and has a significant impact on patients' quality of life. Given the evolving understanding of IBD pathology and management strategies, there is an urgent need to review the recent research findings. In this …
Xianglian pill alleviates ulcerative colitis by inhibiting M1 macrophage polarization via modulation of energy metabolite itaconate
Publication Year: 2024 Source: Phytomedicine PMID: 39467429
No Abstract
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