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Evaluating the association between immunological proteins and common intestinal diseases using a bidirectional two-sample Mendelian randomization study

Publication Year: 2024 Source: Cytokine PMID: 39467484 DOI: 10.1016/j.cyto.2024.156788

Dysregulation of intestinal homeostasis, characterized by imbalanced immunological proteins, contributes to the pathogenesis of common intestinal diseases, e.g., irritable bowel syndrome (IBS), inflammatory bowel disease (IBD), and colorectal cancer (CRC). However, the potential causal relationships between specific immunological proteins and these diseases remain to be fully elucidated. In this study, …

Proactive therapeutic drug monitoring of biologic drugs in adult patients with inflammatory bowel disease, inflammatory arthritis, or psoriasis: a clinical practice guideline

Publication Year: 2024 Source: BMJ PMID: 39467592

No Abstract

Galactooligosaccharides and Limosilactobacillus reuteri synergistically alleviate gut inflammation and barrier dysfunction by enriching Bacteroides acidifaciens for pentadecanoic acid biosynthesis

Publication Year: 2024 Source: Nat Commun PMID: 39468026

No Abstract

Relationship Between Social Isolation, Loneliness and Psychological Well-Being in Inflammatory Bowel Disease Patients: The Mediating Role of Disease Activity Social Isolation in Inflammatory Bowel Disease

Publication Year: 2024 Source: J Clin Nurs PMID: 39468919 DOI: 10.1111/jocn.17509

AIM: To evaluate the relationship between social isolation, loneliness and psychological well-being in patients with inflammatory bowel disease (IBD). Additionally, we examined the mediating effect of disease activity on the relationships between social isolation, loneliness and psychological well-being. DESIGN: Cross-sectional descriptive study. METHODS: A total of 218 participants were recruited …

The biogeography of the mucosa-associated microbiome in health and disease

Publication Year: 2024 Source: Front Microbiol PMID: 39469457 DOI: 10.3389/fmicb.2024.1454910

INTRODUCTION: Little is known about the biogeography of the mucosa associated microbiome (MAM) in patients with inflammatory bowel disease (IBD) versus controls in different segments of the gastrointestinal tract, as well as the links between the MAM, gastrointestinal symptoms, and use of proton pump inhibitors (PPI). METHODS: We recruited 59 …

Genomic insights and functional evaluation of Lacticaseibacillus paracasei EG005: a promising probiotic with enhanced antioxidant activity

Publication Year: 2024 Source: Front Microbiol PMID: 39469458

No Abstract

High-Dimensional Bayesian Semiparametric Models for Small Samples: A Principled Approach to the Analysis of Cytokine Expression Data

Publication Year: 2024 Source: Biom J PMID: 39470109

No Abstract

Management of ulcerative colitis: where are we at and where are we heading?

Publication Year: 2024 Source: Expert Rev Gastroenterol Hepatol PMID: 39470444

No Abstract

Cysteine cathepsins and autoimmune diseases: A bidirectional Mendelian randomization

Publication Year: 2024 Source: Medicine (Baltimore) PMID: 39470488

No Abstract

Dose escalation of biologics in biologic-naive patients with Crohn's disease: Outcomes from the ODESSA-CD study

Publication Year: 2024 Source: J Manag Care Spec Pharm PMID: 39471266

No Abstract

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