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Predicting complications in paediatric ulcerative colitis: A longitudinal multicentre cohort study

Publication Year: 2024 Source: Aliment Pharmacol Ther PMID: 39485058

No Abstract

Oral administration of Lactobacillus casei DG® after ileostomy closure in restorative proctocolectomy: a randomized placebo-controlled trial (microbiota and immune microenvironment in pouchitis -MEP1)

Publication Year: 2024 Source: Gut Microbes PMID: 39485259

No Abstract

Anti-inflammatory activity of Ziziphus jujuba hydroalcoholic extract in acetic acid-induced ulcerative colitis model

Publication Year: 2024 Source: J Complement Integr Med PMID: 39485260

No Abstract

Effects of water-insoluble wheat bran-fraction powder on disease activity and caecal microbiota in dextran sodium sulphate-induced inflammatory bowel disease mouse model

Publication Year: 2024 Source: Mol Biol Rep PMID: 39485667 DOI: 10.1007/s11033-024-10045-2

BACKGROUND: Water-soluble arabinoxylan exerts anti-colitic effect and exhibits ameliorative activity in an inflammatory bowel disease (IBD) mouse model. Water soluble fibre from wheat bran (WB) also exhibits anti-colitic effect. However, arabinoxylan is a primary compound of insoluble polysaccharide (hemicellulose) in WB. This study aimed to clarify the anti-IBD effects of …

FBXO22 inhibits colitis and colorectal carcinogenesis by regulating the degradation of the S2448-phosphorylated form of mTOR

Publication Year: 2024 Source: Proc Natl Acad Sci U S A PMID: 39485803 DOI: 10.1073/pnas.2402035121

Inflammatory bowel disease (IBD) is a considerable threat to human health with a significant risk for colorectal cancer (CRC). However, currently, both the molecular pathogenesis and therapeutic treatment of IBD remain limited. In this report, using both systemic and intestinal epithelium-specific gene knockout mouse models, we demonstrate that FBXO22, a …

Reasons for reduced reproduction after colectomy in women with ulcerative colitis

Publication Year: 2024 Source: Scand J Gastroenterol PMID: 39486440

No Abstract

Development of interleukin-27 recombinant Lactococcus lactis and its efficacy in treating psoriasis and colitis in mice

Publication Year: 2024 Source: Int J Biol Macromol PMID: 39486722 DOI: 10.1016/j.ijbiomac.2024.137113

Psoriasis and inflammatory bowel disease (IBD) are chronic immune-mediated diseases that adversely affect patients' quality of life. Interleukin (IL)-27 plays an important role in a variety of infectious diseases, autoimmune disorders, and cancers. However, its therapeutic effects in psoriasis and colitis remain underexplored. In this study, we evaluated the therapeutic …

Tarm1 may affect colitis by regulating macrophage M1 polarization in a mouse colitis model

Publication Year: 2024 Source: Pediatr Res PMID: 39487321

No Abstract

Clinical analysis and identification of pediatric patients with colonic ulceration

Publication Year: 2024 Source: BMC Pediatr PMID: 39487408 DOI: 10.1186/s12887-024-05174-3

BACKGROUND: A wide variety of diseases mimic inflammatory bowel disease (IBD). This study aimed to reduce the misdiagnosis among children with colonic ulcers. METHODS: Eighty-six pediatric patients with colonic ulcers detected by colonoscopy were enrolled in the retrospective study. Children were divided into different groups according to the final diagnosis. …

Adropin regulates macrophage phenotype via PPARγ signalling: A preliminary study of adropin and Crohn's disease

Publication Year: 2024 Source: Scand J Immunol PMID: 39487564

No Abstract

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