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Incidence, prevalence and clinical presentation of inflammatory bowel diseases in Northern France: a 30-year population-based study
Publication Year: 2024 Source: Lancet Reg Health Eur PMID: 39478988 DOI: 10.1016/j.lanepe.2024.101097
BACKGROUND: In industrialized countries, the incidence of inflammatory bowel disease (IBD) appears stabilized. This study examined the incidence and phenotype of IBD in Northern France over a 30-year period. METHODS: Including all IBD patients recorded in the EPIMAD population-based registry from 1988 to 2017 in Northern France, we described the …
The role of gut microbiome in mediating the effect of inflammatory bowel disease on hypertension: a two-step, two-sample Mendelian randomization study
Publication Year: 2024 Source: Front Cardiovasc Med PMID: 39479396 DOI: 10.3389/fcvm.2024.1396973
OBJECTIVE: Investigating the causal connection that exists between inflammatory bowel disease (IBD) and hypertension (HT). To gain a deeper insight into the correlation among IBD, gut microbiota, and HT, we conducted a two-step, two-sample Mendelian randomization study. METHODS: An investigation of genome-wide association study (GWAS) summary-level data was utilized to …
Multiomics analysis reveals the potential mechanism of high-fat diet in dextran sulfate sodium-induced colitis mice model
Publication Year: 2024 Source: Food Sci Nutr PMID: 39479684 DOI: 10.1002/fsn3.4426
A high-fat diet (HFD) is recognized as an important contributor to inflammatory bowel disease (IBD). However, the precise underlying mechanism of HFD on IBD remains elusive. This study aimed to investigate the potential mechanism by which HFD affects IBD using 16S rRNA-sequencing and RNA-seq technology. Results indicated that HFD-treated mice …
osa-miR168a, a Plant miRNA That Survives the Process of In Vivo Food Digestion, Attenuates Dextran Sulfate Sodium-Induced Colitis in Mice by Oral Administration
Publication Year: 2024 Source: J Agric Food Chem PMID: 39480689
No Abstract
Pectin from comfrey roots alleviate DSS-induced ulcerative colitis in mice through modulating the intestinal barrier
Publication Year: 2024 Source: Int J Biol Macromol PMID: 39481739
No Abstract
Investigating the causal links between obstructive sleep apnea and gastrointestinal diseases mediated by metabolic syndrome through mendelian randomization
Publication Year: 2024 Source: Sci Rep PMID: 39482370
No Abstract
[Diagnosis and treatment of fatigue in patients with inflammatory bowel disease]
Publication Year: 2024 Source: MMW Fortschr Med PMID: 39482522
No Abstract
Global research trends and hotspots on human intestinal fungi and health: a bibliometric visualization study
Publication Year: 2024 Source: Front Cell Infect Microbiol PMID: 39483119
No Abstract
Human gut commensal Alistipes timonensis modulates the host lipidome and delivers anti-inflammatory outer membrane vesicles to suppress colitis in an Il10 -deficient mouse model
Publication Year: 2024 Source: bioRxiv PMID: 39484420 DOI: 10.1101/2024.10.23.619966
Correlative studies have linked human gut microbes to specific health conditions. Alistipes is one such microbial genus negatively linked to inflammatory bowel disease (IBD). However, the protective role of Alistipes in IBD has not been studied and the underlying molecular mechanisms also remain unknown. In this study, colonization of Il10 …
Understanding disease-associated metabolic changes in human colon epithelial cells using i ColonEpithelium metabolic reconstruction
Publication Year: 2024 Source: bioRxiv PMID: 39484551
No Abstract
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