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Fine-mapping and molecular characterisation of primary sclerosing cholangitis genetic risk loci

Publication Year: 2024 Source: Nat Commun PMID: 39505854

No Abstract

Colibactin-driven colon cancer requires adhesin-mediated epithelial binding

Publication Year: 2024 Source: Nature PMID: 39506107

No Abstract

Computed tomography enterography radiomics and machine learning for identification of Crohn's disease

Publication Year: 2024 Source: BMC Med Imaging PMID: 39506676

No Abstract

Homocysteine aggravates intestinal inflammation through promotion of 5-LOX and COX-2 in IBD

Publication Year: 2024 Source: Eur J Med Res PMID: 39506850 DOI: 10.1186/s40001-024-02125-7

BACKGROUND: Homocysteine (Hcy) is a pro-inflammatory molecule that has the potential to induce oxidative damage to cells and stimulate the release of inflammatory mediators. Hcy has been observed to enhance the production of inflammatory agents in vascular endothelial cells. However, the impact of Hcy on intestinal mucosal inflammation remains largely …

Laparoscopic sigmoid colectomy with primary anastomosis for experimental modeling in the nonhuman primate

Publication Year: 2024 Source: Ann Transl Med PMID: 39507443

No Abstract

Immediate Infusion Reaction to Intravenous Risankizumab-rzaa but Subsequent Tolerance to Subcutaneous Risankizumab-rzaa

Publication Year: 2024 Source: ACG Case Rep J PMID: 39507504 DOI: 10.14309/crj.0000000000001546

Risankizumab-rzaa (RZA) is a fully human immunoglobulin G monoclonal antibody (Mab) which has fewer immunogenic concerns compared with chimeric Mabs. The pivotal trials of RZA found no significant differences in infusion reactions between drug and placebo. This case illustrates successful transition to subcutaneous RZA following a serious hypersensitivity reaction to …

Dramatic Changes in Thiopurine Metabolite Levels in a Patient With Inflammatory Bowel Disease Treated With Tirzepatide for Weight Loss

Publication Year: 2024 Source: ACG Case Rep J PMID: 39507506

No Abstract

The Current Role of Imaging in the Diagnosis of Inflammatory Bowel Disease and Detection of Its Complications: A Systematic Review

Publication Year: 2024 Source: Cureus PMID: 39507607 DOI: 10.7759/cureus.73134

Inflammatory bowel disease (IBD) encompasses complex gastrointestinal (GI) conditions, primarily Crohn's disease (CD) and ulcerative colitis (UC), requiring precise imaging for effective diagnosis and management of complications. This systematic review aimed to evaluate the current role of imaging modalities in diagnosing IBD and detecting related complications. The review adhered to …

[α-Cyperone Antagonizes Intestinal Mucosal Inflammatory Response Through Modulation of TLR4/NF-κB Signaling Pathway to Alleviate Crohn's Disease-Like Colitis in Mice]

Publication Year: 2024 Source: Sichuan Da Xue Xue Bao Yi Xue Ban PMID: 39507974

No Abstract

[Isongifolene Improves Crohn's Disease-Like Colitis in Mice by Reducing Apoptosis of Intestinal Epithelial Cells]

Publication Year: 2024 Source: Sichuan Da Xue Xue Bao Yi Xue Ban PMID: 39507978

No Abstract

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