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The Hydrophobic Amino Acid-Rich Fish Collagen Peptide Ameliorates Dextran Sulfate Sodium-Induced Ulcerative Colitis in Mice via Repairing the Intestinal Barrier, Regulating Intestinal Flora and AA Metabolism
Publication Year: 2024 Source: J Agric Food Chem PMID: 39514440
No Abstract
Macrophage LRRK2 hyperactivity impairs autophagy and induces Paneth cell dysfunction
Publication Year: 2024 Source: Sci Immunol PMID: 39514635
No Abstract
Polymethoxylated flavones for modulating signaling pathways in inflammation
Publication Year: 2024 Source: Int Immunopharmacol PMID: 39515044 DOI: 10.1016/j.intimp.2024.113522
Aberrant signaling pathways play a crucial role in the pathogenesis of various diseases, including inflammatory disorders and autoimmune conditions. Polymethoxylated flavones (PMFs), a class of natural compounds found in citrus fruits, have obtained increasing attention for their potential therapeutic effects in modulating inflammatory responses. Although significant progress has been made …
Metabolomics reveals the metabolic disturbance caused by arsenic in the mouse model of inflammatory bowel disease
Publication Year: 2024 Source: Ecotoxicol Environ Saf PMID: 39515204 DOI: 10.1016/j.ecoenv.2024.117305
Arsenic exposure has long been a significant global health concern due to its association with various human diseases. The adverse health effects of arsenic can be influenced by multiple factors, resulting in considerable individual variability. Individuals with inflammatory bowel disease (IBD) are particularly vulnerable to the effects of toxin exposure, …
Infliximab monotherapy for ulcerative colitis-related severe enteritis following colectomy in a paediatric patient
Publication Year: 2024 Source: BMJ Case Rep PMID: 39515825
No Abstract
Recurrence rates after strictureplasty for small bowel Crohn's disease remain high in the era of biologics
Publication Year: 2024 Source: Colorectal Dis PMID: 39515997
No Abstract
Efficacy of Nigella sativa seed oil against psychophysical stress induced irritable bowel syndrome and anxiety-like symptoms in Wistar rats
Publication Year: 2024 Source: Psychopharmacology (Berl) PMID: 39516296
No Abstract
Efficacy and Safety of GLP-1 Agonists on Metabolic Parameters in Non-diabetic Patients with Inflammatory Bowel Disease
Publication Year: 2024 Source: Dig Dis Sci PMID: 39516435 DOI: 10.1007/s10620-024-08720-2
BACKGROUND: Obesity in patients with IBD is increasing, accompanied by an increase in metabolic comorbidities. Although GLP-1 agonists have shown promise in weight reduction, their efficacy and safety in patients with IBD are underexplored. This study evaluated the impact of GLP-1-based therapies on weight loss and metabolic parameters in non-diabetic …
Stenosing Crohn's disease patients display gut autophagy/oxidative stress imbalance
Publication Year: 2024 Source: Sci Rep PMID: 39516576 DOI: 10.1038/s41598-024-79308-z
In this pilot study, we assessed the role of autophagy in Crohn's Disease (CD), particularly in patients with a stenosing phenotype. Through the analysis of biopsied specimens from 36 patients, including 11 controls and 25 CD patients, categorized into inflammatory and stenosing groups, we identified a significant reduction in the …
Exploring the mechanism of Suxin Hugan Fang in treating ulcerative colitis based on network pharmacology
Publication Year: 2024 Source: Sci Rep PMID: 39516633
No Abstract
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