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Luteolin ameliorates ulcerative colitis in mice via reducing the depletion of NCR(+)ILC3 through Notch signaling pathway
Publication Year: 2024 Source: Chin J Nat Med PMID: 39510641
No Abstract
Impact of chronic opioid use on acute health care utilization in children with IBD and arthritis: a retrospective cohort study
Publication Year: 2024 Source: BMC Pediatr PMID: 39511521 DOI: 10.1186/s12887-024-05206-y
BACKGROUND: Opioid use is non-trivial in children with inflammatory bowel disease (IBD) and arthritis, and options are limited for pain management. We aimed to determine the impacts of chronic opioid use on acute care utilization in children with both IBD and arthritis in United States. METHODS: Participants less than 18 …
Prolonged Fever After the Treatment of Ulcerative Colitis in an Adolescent
Publication Year: 2024 Source: Pediatrics PMID: 39512069
No Abstract
Evaluation Recovery of Ulcerative Colitis with a Lactobacillus Cocktail Derived from Traditional Dairy Products: In vivo Study
Publication Year: 2024 Source: Adv Biomed Res PMID: 39512406
No Abstract
Cell Membrane-Coated Nanotherapeutics for the Targeted Treatment of Acute and Chronic Colitis
Publication Year: 2024 Source: Biomater Res PMID: 39512421 DOI: 10.34133/bmr.0102
Integrin alpha4beta1 and alpha4beta7 are overexpressed in macrophages and leukocytes and play important roles in mediating cell homing and recruitment to inflammatory tissues. Herein, to enhance the targeting ability of nanotherapeutics for inflammatory bowel disease (IBD) treatment, cyclosporine A-loaded nanoparticles (CsA NPs) were coated with macrophage membranes (MM-CsA NPs) or …
Global burden of inflammatory bowel disease in the elderly: trends from 1990 to 2021 and projections to 2051
Publication Year: 2024 Source: Front Aging PMID: 39512627 DOI: 10.3389/fragi.2024.1479928
BACKGROUND: This study aims to analyze the historical trends of inflammatory bowel disease (IBD) burden in the elderly from 1990 to 2021 and forecast future trends up to 2051. METHODS: Data from the Global Burden of Disease Study 2021 were utilized. Age-standardized rates (ASR) for incidence, prevalence, mortality, and disability-adjusted …
Unequal causality between autoimmune thyroiditis and inflammatory bowel disease: a Mendelian randomization study
Publication Year: 2024 Source: Front Endocrinol (Lausanne) PMID: 39512756 DOI: 10.3389/fendo.2024.1387482
OBJECTIVE: This study aims to analyze the causal relationship between autoimmune thyroiditis (AIT) and inflammatory bowel disease (IBD) using bidirectional Mendelian randomization (MR). METHODS: Single nucleotide polymorphisms were obtained from FinnGen. Exposure-outcome causality was assessed using inverse variance weighted, MR-Egger, and weighted median. MR-Egger intercept, Cochran's Q, and leave-one-out sensitivity …
Effect of Bacillus clausii in attenuating symptoms of DSS-induced ulcerative colitis by modulating NFkB pathway and oxidative stress in mice
Publication Year: 2024 Source: Clin Exp Pharmacol Physiol PMID: 39513300
No Abstract
Serum electrolyte abnormalities in cats with chronic inflammatory enteropathy
Publication Year: 2024 Source: J Vet Intern Med PMID: 39513556
No Abstract
Discovery of Thiazole Carboxamides as Novel Vanin-1 Inhibitors for Inflammatory Bowel Disease Treatment
Publication Year: 2024 Source: J Med Chem PMID: 39514323 DOI: 10.1021/acs.jmedchem.4c01838
Inflammatory bowel disease (IBD) is a clinically heterogeneous disease demanding more therapeutic targets and intervention strategies. Vanin-1, an oxidative stress-regulating protein, has emerged as a promising target for alleviating inflammation and oxidative stress. In this study, a series of thiazole carboxamide derivatives as vanin-1 inhibitors were designed and synthesized. The …
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