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Criterion Validity of Screening Tools and Field-Based Tests for Health-Related Physical Fitness in Inflammatory Bowel Disease
Publication Year: 2024 Source: Dig Dis Sci PMID: 39425857 DOI: 10.1007/s10620-024-08682-5
BACKGROUND: Monitoring health-related physical fitness (HRPF) may benefit proactive Inflammatory Bowel Disease (IBD) management. However, knowledge regarding HRPF in patients with IBD is limited and gold standard tests are impractical for widespread use, necessitating simpler methods. AIM: This study evaluated the criterion validity of screening tools and field-based tests compared …
Butyrate attenuates intestinal inflammation in Crohn's disease by suppressing pyroptosis of intestinal epithelial cells via the cGSA-STING-NLRP3 axis
Publication Year: 2024 Source: Int Immunopharmacol PMID: 39426229
No Abstract
Estrogen receptor α aggravates intestinal inflammation via promoting the activation of NLRP3 inflammasome
Publication Year: 2024 Source: Int Immunopharmacol PMID: 39426237 DOI: 10.1016/j.intimp.2024.113425
Activation of the NLRP3 inflammasome and estrogen receptor alpha (ERalpha) has been shown to increase the risk of inflammatory bowel diseases (IBD) or promote disease recurrence. In previous work, we demonstrated that ERalpha regulated the transcription of NLRP3. However, the precise mechanism by which ERalpha modulates NLRP3 in IBD models …
Bioinspired core-shell microparticle for dual-delivery of prebiotic and probiotic for the treatment of ulcerative colitis
Publication Year: 2024 Source: J Control Release PMID: 39426504
No Abstract
TIPE2 aggravates experimental colitis and disrupts intestinal epithelial barrier integrity by activating JAK2/STAT3/SOCS3 signal pathway
Publication Year: 2024 Source: Exp Cell Res PMID: 39426612
No Abstract
The reverse transsulfuration pathway affects the colonic microbiota and contributes to colitis in mice
Publication Year: 2024 Source: Amino Acids PMID: 39427081
No Abstract
Fecal glycoprotein 2 is a marker of gut microbiota dysbiosis and systemic inflammation
Publication Year: 2024 Source: Gut Pathog PMID: 39427219 DOI: 10.1186/s13099-024-00657-1
BACKGROUND: Antimicrobial autoantigenic glycoprotein 2 (GP2) is an important component of the innate immune system which originates from the exocrine pancreas as well as from the small intestines. The relationship of GP2 with the intestinal microbiome as well as the systemic implications of increased fecal GP2 levels are, however, still …
EBV infection alters DNA methylation in primary human colon cells: A path to inflammation and carcinogenesis?
Publication Year: 2024 Source: Biochim Biophys Acta Gene Regul Mech PMID: 39427708 DOI: 10.1016/j.bbagrm.2024.195064
Epstein-Barr Virus (EBV) is associated with several types of human cancers, and changes in DNA methylation are reported to contribute to viral-driven carcinogenesis, particularly in cancers of epithelial origin. In a previous study, we demonstrated that EBV infects human primary colonic cells (HCoEpC) and replicates within these cells, leading to …
Structural characterization of the polysaccharides from Atractylodes chinensis (DC.) Koidz. and the protective effection against alcohol-induced intestinal injury in rats
Publication Year: 2024 Source: Int J Biol Macromol PMID: 39427804
No Abstract
Curcumin-loaded polysaccharide microparticles alleviated DSS-induced ulcerative colitis by improving intestinal microecology and regulating MAPK/NF-κB/Nrf2/NLRP3 pathways
Publication Year: 2024 Source: Int J Biol Macromol PMID: 39427805
No Abstract
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