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Concurrent chronic kidney disease in patients with inflammatory bowel disease, a systematic review and meta-analysis

Publication Year: 2024 Source: Front Med (Lausanne) PMID: 39421866 DOI: 10.3389/fmed.2024.1485087

INTRODUCTION: Inflammatory bowel disease (IBD) is a multi-organ autoimmune disease that commonly affects the gastrointestinal tract, but can also affect other organs throughout the body. Less is known, however, about kidney involvement in IBD. Although IBD has been associated with chronic kidney disease (CKD) and end-stage renal disease (ESRD), these …

Treatment outcomes of mild to moderate Clostridioides difficile infection in inflammatory bowel disease: an Australian experience

Publication Year: 2024 Source: Intern Med J PMID: 39422325 DOI: 10.1111/imj.16545

BACKGROUND: The incidence of Clostridioides difficile infection (CDI) in inflammatory bowel disease (IBD) is rising and associated with adverse outcomes. Optimal treatment for CDI in IBD remains unknown, with various organisations suggesting vancomycin as first-line therapy. AIM: To compare treatment outcomes for metronidazole versus vancomycin in mild to moderate CDI …

Formononetin alleviates ulcerative colitis via reshaping the balance of M1/M2 macrophage polarization in a gut microbiota-dependent manner

Publication Year: 2024 Source: Phytomedicine PMID: 39423480

No Abstract

Scutellarin alleviated ulcerative colitis through gut microbiota-mediated cAMP/PKA/NF-κB pathway

Publication Year: 2024 Source: Biochem Biophys Res Commun PMID: 39423571

No Abstract

Palmatine alleviates inflammation and modulates ferroptosis against dextran sulfate sodium (DSS)-induced ulcerative colitis

Publication Year: 2024 Source: Int Immunopharmacol PMID: 39423661

No Abstract

Association between nutritional status assessed by body mass index and Crohn's disease phenotype: A Nation-wide analysis

Publication Year: 2024 Source: Clin Nutr ESPEN PMID: 39423922 DOI: 10.1016/j.clnesp.2024.09.033

BACKGROUND & AIMS: Incidence of obesity and Crohn's disease (CD) is increasing globally. Therefore, understanding any associations between adiposity and disease phenotype is crucial. We aimed explore the relationship between nutritional status measured by body mass index (BMI) and phenotypes of CD using a large national recallable data set. METHODS: …

Advances in carbohydrate-based nanoparticles for targeted therapy of inflammatory bowel diseases: A review

Publication Year: 2024 Source: Int J Biol Macromol PMID: 39423983 DOI: 10.1016/j.ijbiomac.2024.136392

The incidence of inflammatory bowel disease (IBD), a chronic gastrointestinal disorder, is rapidly increasing worldwide. Unfortunately, the current therapies for IBD are often hindered by premature drug release and undesirable side effects. With the advancement of nanotechnology, the innovative targeted nanotherapeutics are explored to ensure the accurate delivery of drugs …

The value of assessing deep disease healing by probe-based confocal laser endomicroscopy and histology for long-term prognosis of ulcerative colitis

Publication Year: 2024 Source: J Gastroenterol Hepatol PMID: 39425247

No Abstract

The impact of achieving remission in inflammatory bowel disease on plasma matrix γ-carboxyglutamate protein levels

Publication Year: 2024 Source: Egypt J Immunol PMID: 39425625

Matrix gamma-carboxyglutamic acid (MGLA) protein is a vitamin K dependent peptide which contributes to the immunomodulatory activity of mesenchymal stromal cells. There is a possible association between MGLA protein and inflammatory bowel disease (IBD) which is divided into Crohn's disease (CD) and ulcerative colitis (UC). However, little is known about …

Comparative Efficacy of Advanced Therapies for Management of Moderate-to-Severe Ulcerative Colitis: 2024 American Gastroenterological Association Evidence Synthesis

Publication Year: 2024 Source: Gastroenterology PMID: 39425738

No Abstract

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