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High Rate of Seroprotection With Heplisav-B in Patients With Inflammatory Bowel Disease
Publication Year: 2024 Source: J Clin Gastroenterol PMID: 40424081 DOI: 10.1097/MCG.0000000000002098
OBJECTIVE: Patients with inflammatory bowel disease (IBD) are commonly treated with immunosuppressive therapies that increase the risk for infections, including hepatitis B (HepB) virus. Adult patients with IBD have suboptimal seroprotection rates after vaccination with a 3-dose recombinant recombinant HepB vaccine. Heplisav-B is an adjuvanted 2-dose HepB series that is …
STRUCTURAL EVALUATION OF INFLAMMATORY BOWEL DISEASE COMPREHENSIVE CARE UNITS IN BRAZIL
Publication Year: 2024 Source: Arq Gastroenterol PMID: 38511798 DOI: 10.1590/S0004-2803.24612023-166
BACKGROUND: The most efficient way to prevent complications from inflammatory bowel disease (IBD) is to provide patients with optimized care. Nonetheless, in Brazil, there is no validated methodology for evaluating health services recognized as comprehensive care units (CCU), making it difficult to assess the quality of care provided. OBJECTIVE: To …
[Prunetin inhibits TLR4/MyD88 pathway to attenuate intestinal epithelial inflammatory response and ameliorate mouse Crohn's disease-like colitis]
Publication Year: 2024 Source: Xi Bao Yu Fen Zi Mian Yi Xue Za Zhi PMID: 38512029
No Abstract
Assessing the economics of biologic and small molecule therapies for the treatment of moderate to severe ulcerative colitis in Japan: a cost per responder analysis of upadacitinib
Publication Year: 2024 Source: J Med Econ PMID: 38512101
No Abstract
Upadacitinib in Crohn's disease
Publication Year: 2024 Source: Expert Opin Pharmacother PMID: 38512115 DOI: 10.1080/14656566.2024.2333964
INTRODUCTION: The small molecule and oral selective and reversible Janus kinase (JAK) inhibitor upadacitinib has been approved for the treatment of moderate to severe active Crohn's disease (CD) in adult patients since April 2023 by EMA/FDA. AREAS COVERED: The approval is based on the two induction studies a maintenance study …
Dietary carbohydrates regulate intestinal colonization and dissemination of Klebsiella pneumoniae
Publication Year: 2024 Source: J Clin Invest PMID: 38512401
No Abstract
Relationship Between the Frequency of Bowel Movements and Fecal Bacteroides in Japanese Women
Publication Year: 2024 Source: Plant Foods Hum Nutr PMID: 38512409
No Abstract
Which magnetic resonance imaging feature is associated with treatment response in perianal fistulizing Crohn's disease?
Publication Year: 2024 Source: Abdom Radiol (NY) PMID: 38512515
No Abstract
Unmet needs of drugs for irritable bowel syndrome and inflammatory bowel diseases: interest of vagus nerve stimulation and hypnosis
Publication Year: 2024 Source: Inflammopharmacology PMID: 38512653
No Abstract
Retinoid orphan receptor gamma t (rorγt) promotes inflammatory eosinophilia but is dispensable for innate immune-mediated colitis
Publication Year: 2024 Source: PLoS One PMID: 38512959 DOI: 10.1371/journal.pone.0300892
Inflammatory bowel diseases (IBD) result from uncontrolled inflammation in the intestinal mucosa leading to damage and loss of function. Both innate and adaptive immunity contribute to the inflammation of IBD and innate and adaptive immune cells reciprocally activate each other in a forward feedback loop. In order to better understand …
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