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Autoimmune pancreatitis: Cornerstones and future perspectives

Publication Year: 2024 Source: World J Gastroenterol PMID: 38516247

No Abstract

ERCC4: a potential regulatory factor in inflammatory bowel disease and inflammation-associated colorectal cancer

Publication Year: 2024 Source: Front Endocrinol (Lausanne) PMID: 38516408 DOI: 10.3389/fendo.2024.1348216

The pathogenesis of inflammatory bowel disease (IBD) remains unclear and is associated with an increased risk of developing colitis-associated cancer (CAC). Under sustained inflammatory stimulation in the intestines, loss of early DNA damage response genes can lead to tumor formation. Many proteins are involved in the pathways of DNA damage …

The Role of Gut Microbiome in the Pathogenesis and the Treatment of Inflammatory Bowel Diseases

Publication Year: 2024 Source: Cureus PMID: 38516478 DOI: 10.7759/cureus.54569

Inflammatory bowel disease (IBD), which includes ulcerative colitis and Crohn's disease, is a chronic condition characterized by inflammation of the gastrointestinal tract. Its exact cause is unknown, but it's thought to result from a dysregulated immune response influenced by various factors, including changes in the intestinal microbiota, diet, lifestyle, and …

Gallic acid attenuates LPS-induced inflammation in Caco-2 cells by suppressing the activation of the NF-κB/MAPK signaling pathway

Publication Year: 2024 Source: Acta Biochim Biophys Sin (Shanghai) PMID: 38516705 DOI: 10.3724/abbs.2024008

Inflammatory bowel disease (IBD) is a chronic inflammatory disease characterized by intestinal barrier dysfunction, inflammatory synergistic effects and excessive tissue injury. Gallic acid (GA) is renowned for its remarkable biological activity, encompassing anti-inflammatory and antioxidant properties. However, the underlying mechanisms by which GA protects against intestinal inflammation have not been …

Prevalence estimates of tuberculosis infection in adults in Denmark: a retrospective nationwide register-based cross-sectional study, 2010 to 2018

Publication Year: 2024 Source: Euro Surveill PMID: 38516789 DOI: 10.2807/1560-7917.ES.2024.29.12.2300590

BackgroundTuberculosis (TB) elimination requires identifying and treating persons with TB infection (TBI).AimWe estimate the prevalence of positive interferon gamma release assay (IGRA) tests (including TB) and TBI (excluding TB) in Denmark based on TBI screening data from patients with inflammatory bowel disease (IBD) or inflammatory rheumatic disease (IRD).MethodsUsing nationwide Danish …

Leukocyte dysfunction and reduced CTLA-4 expression are associated with perianal Crohn's disease

Publication Year: 2024 Source: Clin Exp Immunol PMID: 38517030

No Abstract

Investigating the association between the tissue expression of miRNA-101, JAK2/STAT3 with TNF-α, IL-6, IL-1β, and IL-10 cytokines in the ulcerative colitis patients

Publication Year: 2024 Source: Immun Inflamm Dis PMID: 38517042 DOI: 10.1002/iid3.1224

BACKGROUND: Ulcerative colitis (UC) is a chronic inflammatory bowel disease caused by numerous factors, such as immune system dysfunction and genetic factors. MicroRNAs (miRNAs) play a crucial role in UC pathogenesis, particularly via the JAK-STAT pathway. Our aim was to investigate the association between miRNA-101 and JAK2-STAT3 signaling pathway with …

Expanded spectrum of varicella disease and the need for vaccination in India

Publication Year: 2024 Source: Hum Vaccin Immunother PMID: 38517089

No Abstract

Primary Sclerosing Cholangitis: Gender Effects in Valencia's Low-Prevalence Region

Publication Year: 2024 Source: Dig Dis Sci PMID: 38517562

No Abstract

Efficacy and safety of tofacitinib for chronic plaque psoriasis and psoriatic arthritis: a systematic review and meta-analysis of randomized controlled trials

Publication Year: 2024 Source: Clin Rheumatol PMID: 38517652

No Abstract

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