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Indole-3-acetic acid alleviates DSS-induced colitis by promoting the production of R-equol from Bifidobacterium pseudolongum
Publication Year: 2024 Source: Gut Microbes PMID: 38528729 DOI: 10.1080/19490976.2024.2329147
BACKGROUND: Inflammatory bowel disease (IBD) is characterized by immune-mediated, chronic inflammation of the intestinal tract. The occurrence of IBD is driven by the complex interactions of multiple factors. The objective of this study was to evaluate the therapeutic effects of IAA in colitis. METHOD: C57/BL6 mice were administered 2.5% DSS …
Nonextractable Polyphenols from Fu Brick Tea Alleviates Ulcerative Colitis by Controlling Colon Microbiota-Targeted Release to Inhibit Intestinal Inflammation in Mice
Publication Year: 2024 Source: J Agric Food Chem PMID: 38528736
No Abstract
Coincidence of antibodies against Hwp1 and ASCA, two distinct molecular targets of Candida albicans, reinforces the link between this fungal species and coeliac disease
Publication Year: 2024 Source: Virulence PMID: 38528835
No Abstract
Risk of Primary Gastrointestinal Lymphoma in Patients With Inflammatory Conditions Exposed to Tumor Necrosis Factor Alpha Inhibitors and Immunomodulators: A Case-Control Study
Publication Year: 2024 Source: Crohns Colitis 360 PMID: 38528940
No Abstract
Intestinal Flora Imbalance Induced by Antibiotic Use in Rats
Publication Year: 2024 Source: J Inflamm Res PMID: 38528993 DOI: 10.2147/JIR.S447098
AIM: This study aims to explore the effect of different doses of antibiotics on rats in order to observe alterations in their fecal microbiota, inflammatory changes in the colonic mucosa and four types of inflammatory markers in blood serum. METHODS: Our methodology involved separating 84 female Sprague Dawley rats into …
Phylogeographic analysis reveals extensive genetic variation of native grass Elymus nutans (Poaceae) on the Qinghai-Tibetan plateau
Publication Year: 2024 Source: Front Plant Sci PMID: 38529066 DOI: 10.3389/fpls.2024.1349641
INTRODUCTION: Elymus nutans holds ecological and pastoral significance due to its adaptability and nutritional value, the Qinghai-Tibet Plateau (QTP) is a key hub for its genetic diversity. To conserve and harness its genetic resources in highland ecosystems, a thorough assessment is vital. However, a comprehensive phylogeographic exploration of E. nutans …
Unlocking the potential of fondaparinux: guideline for optimal usage and clinical suggestions (2023)
Publication Year: 2024 Source: Front Pharmacol PMID: 38529183 DOI: 10.3389/fphar.2024.1352982
Background: Thromboembolic disease is associated with a high rate of disability or death and gravely jeopardizes people's health and places considerable financial pressure on society. The primary treatment for thromboembolic illness is anticoagulant medication. Fondaparinux, a parenteral anticoagulant medicine, is still used but is confusing due to its disparate domestic …
The Role of Inflammatory Biomarkers in Mediating the Effect of Inflammatory Bowel Disease on nonmalignant Digestive System Diseases: A Multivariable Mendelian Randomized Study
Publication Year: 2024 Source: Can J Gastroenterol Hepatol PMID: 38529201 DOI: 10.1155/2024/1266139
BACKGROUND: While observation studies have shown a positive correlation between inflammatory bowel disease (IBD) and the risk of nonmalignant digestive system diseases, a definitive causal relationship has not yet been clearly established. METHODS: Mendelian randomization (MR) was employed to investigate the potential causal association between genetic susceptibility to IBD and …
Mannose enhances intestinal immune barrier function and dextran sulfate sodium salt-induced colitis in mice by regulating intestinal microbiota
Publication Year: 2024 Source: Front Immunol PMID: 38529272 DOI: 10.3389/fimmu.2024.1365457
BACKGROUND: Inflammatory bowel disease (IBD) greatly affects human quality of life. Mannose has been reported to be used to treat IBD, but the mechanism is currently unknown. METHODS: C57/BL mice were used as research subjects, and the mouse acute colitis model was induced using dextran sulfate sodium salt (DSS). After …
Comparative analysis of single-cell transcriptome reveals heterogeneity and commonality in the immune microenvironment of colorectal cancer and inflammatory bowel disease
Publication Year: 2024 Source: Front Immunol PMID: 38529274 DOI: 10.3389/fimmu.2024.1356075
BACKGROUND: During aging, chronic inflammation can promote tumor development and metastasis. Patients with chronic inflammatory bowel diseases (IBD) are at an increased risk of developing colorectal cancer (CRC). However, the molecular mechanism underlying is still unclear. METHODS: We conducted a large-scale single-cell sequencing analysis comprising 432,314 single cells from 92 …
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