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Integrated multi-omics reveal gut microbiota-mediated bile acid metabolism alteration regulating immunotherapy responses to anti-α4β7-integrin in Crohn's disease
Publication Year: 2024 Source: Gut Microbes PMID: 38312103
No Abstract
Exposure to prescribed medication in early life and impacts on gut microbiota and disease development
Publication Year: 2024 Source: EClinicalMedicine PMID: 38312240
No Abstract
Calcific constrictive pericarditis following tumour necrosis factor-alpha inhibition
Publication Year: 2024 Source: Eur Heart J Case Rep PMID: 38313324
No Abstract
Causal linkage between type 2 diabetes mellitus and inflammatory bowel disease: an integrated Mendelian randomization study and bioinformatics analysis
Publication Year: 2024 Source: Front Endocrinol (Lausanne) PMID: 38313367 DOI: 10.3389/fendo.2024.1275699
BACKGROUND: Observational studies have indicated associations between type 2 diabetes mellitus (T2DM) and both colorectal cancer (CRC) and inflammatory bowel disease (IBD). However, the underlying causality and biological mechanisms between these associations remains unclear. METHODS: We conducted a bidirectional Mendelian randomization (MR) analysis employing summary statistics from genome-wide association studies …
Unraveling Epigenetic Interplay between Inflammation, Thrombosis, and Immune-Related Disorders through a Network Meta-analysis
Publication Year: 2024 Source: TH Open PMID: 38313596
No Abstract
Use of curcumin and its nanopreparations in the treatment of inflammatory bowel disease
Publication Year: 2024 Source: World J Gastroenterol PMID: 38314128 DOI: 10.3748/wjg.v30.i3.280
Inflammatory bowel disease (IBD) is a nonspecific inflammatory disease of the intestine that includes Crohn's disease and ulcerative colitis. Because IBD is difficult to heal and easily relapses, it could worsen patient quality of life and increase economic burdens. Curcumin (CUR) is a bioactive component derived from the rhizome of …
SLC6A14 promotes ulcerative colitis progression by facilitating NLRP3 inflammasome-mediated pyroptosis
Publication Year: 2024 Source: World J Gastroenterol PMID: 38314135
No Abstract
The Fundamentals of Inflammatory Bowel Disease Management in Pregnancy: A Practical Review for the Gastroenterologist
Publication Year: 2024 Source: J Can Assoc Gastroenterol PMID: 38314178 DOI: 10.1093/jcag/gwad056
This narrative review explores the management of Inflammatory Bowel Disease (IBD) during pregnancy, emphasizing its unique challenges to maternal and fetal health, particularly within the Canadian Gastroenterology setting. Seven key principles are highlighted: 1) Preconception counselling, aiming for steroid-free remission confirmed by objective markers, should be routine for female IBD …
Bloody Diarrhea in a 27-year-old Man with Adult-onset Still's Disease
Publication Year: 2024 Source: JMA J PMID: 38314407
A 27-year-old man presented with quotidian fever, rash, knee arthralgia, sore throat, and bloody diarrhea. Laboratory findings showed neutrophilia, elevated CRP, ferritin, and liver enzyme levels, and decreased hemoglobin levels. Radiological investigations revealed splenomegaly, systemic lymphadenopathy, thickening of the descending colon wall, and an abnormal uptake in the bone marrow …
No Correlation between Anti-drug Antibodies and Therapeutic Response in Tunisian Patients with Chronic Inflammatory Diseases Treated by TNF Blockers
Publication Year: 2024 Source: Curr Rheumatol Rev PMID: 38314598
No Abstract
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