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Sulforaphane Regulates Macrophage M1/M2 Polarization to Attenuate Macrophage-induced Caco-2 Cell Injury in an Inflammatory Environment

Publication Year: 2024 Source: Iran J Immunol PMID: 38314669 DOI: 10.22034/iji.2024.98644.2580

BACKGROUND: The imbalance between M1 and M2 macrophage activation is closely associated with the pathogenesis of inflammatory bowel diseases (IBDs). Sulforaphane (SFN) plays an important role in the treatment of inflammatory diseases. OBJECTIVE: To investigate the effect of SFN on macrophage polarization and its underlying regulatory mechanism. METHODS: Mouse bone …

Inflammatory Bowel Disease Hospitalizations Are Similar for Patients Receiving Televisit-Delivered Outpatient Care and Those Receiving Traditional In-Person Care

Publication Year: 2024 Source: Am J Gastroenterol PMID: 38314800 DOI: 10.14309/ajg.0000000000002703

INTRODUCTION: The coronavirus disease 2019 pandemic resulted in widespread expansion of telehealth. However, there are concerns that telehealth-delivered outpatient care may limit opportunities for managing complications and preventing hospitalizations for patients with inflammatory bowel disease (IBD). We aimed to assess the association between outpatient IBD care delivered through televisit (video …

Implantation Surgery for Abdominal Vagus Nerve Stimulation and Recording Studies in Awake Rats

Publication Year: 2024 Source: J Vis Exp PMID: 38314807

No Abstract

Major basic protein is a useful marker to distinguish eosinophilic esophagitis from IBD-associated eosinophilia in children

Publication Year: 2024 Source: J Pediatr Gastroenterol Nutr PMID: 38314865 DOI: 10.1002/jpn3.12143

OBJECTIVES: The incidence of eosinophilic esophagitis (EoE) is 3-5 times greater in patients with inflammatory bowel disease (IBD) compared with the general population. This study aimed to differentiate true EoE from esophageal eosinophilia in IBD patients by evaluating expression of major basic protein (MBP) and interleukin-13 (IL-13) in esophageal biopsies. …

Efficacy of infliximab after loss of response of/intolerance to adalimumab in pediatric Crohn's disease: A retrospective multicenter cohort study of the "GETAID pédiatrique"

Publication Year: 2024 Source: J Pediatr Gastroenterol Nutr PMID: 38314896

No Abstract

Long-Term Risk of Myocarditis in Patients With Inflammatory Bowel Disease: A Nationwide Cohort Study in Sweden

Publication Year: 2024 Source: Am J Gastroenterol PMID: 38315442 DOI: 10.14309/ajg.0000000000002701

INTRODUCTION: Despite a suggested link between inflammatory bowel disease (IBD) and myocarditis, the association has not been well established. This study aimed to investigate the long-term risk of myocarditis in patients with IBD. METHODS: This nationwide cohort involved all patients with biopsy-confirmed IBD in Sweden (1969-2017) (n = 83,264, Crohn's …

Psychological symptoms and quality of life in patients with inflammatory bowel disease in China: A multicenter study

Publication Year: 2024 Source: United European Gastroenterol J PMID: 38315582 DOI: 10.1002/ueg2.12532

AIMS: To investigate the current situation of mental psychology and quality of life (QoL) in patients with inflammatory bowel disease (IBD) in China, and analyze the influencing factors. METHODS: A unified questionnaire was developed to collect clinical data on IBD patients from 42 hospitals in 22 provinces from September 2021 …

Label-free electrochemical biosensor for direct detection of Oncostatin M (OSM) inflammatory bowel diseases (IBD) biomarker in human serum

Publication Year: 2024 Source: Talanta PMID: 38316076 DOI: 10.1016/j.talanta.2024.125726

Oncostatin M (OSM) is an interleukin-6 (IL-6) member family cytokine implicated in the pathogenesis of chronic diseases including inflammatory bowel disease (IBD). OSM is a novel diagnostic biomarker over-expressed in the serum of IBD patients. This paper reports on the first electrochemical OSM immunosensor, developed using a multistep fabrication process …

Malignant transformation in fistula after proctosigmoidectomy: A rare complication of long-standing Crohn's disease

Publication Year: 2024 Source: Gastroenterol Hepatol PMID: 38316172

No Abstract

Incidence of herpes zoster in patients with inflammatory bowel disease

Publication Year: 2024 Source: Gastroenterol Hepatol PMID: 38316174 DOI: 10.1016/j.gastrohep.2024.01.011

BACKGROUND: Herpes zoster (HZ) is a prevalent disease caused by the reactivation of the varicella-zoster virus (VZV) and associated with chronic morbidity, particularly with post-herpetic neuralgia (PHN). Inflammatory bowel disease (IBD) has been associated with an increased risk of HZ, mainly when immunosuppressive treatment (IMT) is used. However, studies assessing …

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