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A novel link between chronic inflammation and humanin regulation in children

Publication Year: 2024 Source: Front Endocrinol (Lausanne) PMID: 38322155 DOI: 10.3389/fendo.2023.1142310

OBJECTIVE: Children with inflammatory bowel disease (IBD) often suffer from poor bone growth and impaired bone health. Humanin is a cytoprotective factor expressed in bone and other tissues and we hypothesized that humanin levels are suppressed in conditions of chronic inflammation. To address this, humanin levels were analyzed in serum …

Corrigendum: The immune factors have complex causal regulation effects on inflammatory bowel disease

Publication Year: 2024 Source: Front Immunol PMID: 38322256

No Abstract

Roles of ubiquitin-specific proteases in inflammatory diseases

Publication Year: 2024 Source: Front Immunol PMID: 38322269

No Abstract

Exploring the role of IL-1β in inflammatory bowel disease pathogenesis

Publication Year: 2024 Source: Front Med (Lausanne) PMID: 38323035 DOI: 10.3389/fmed.2024.1307394

Interleukin 1beta (IL-1beta) is a significant mediator of inflammation and tissue damage in IBD. The balance between IL-1beta and its endogenous inhibitor-IL-1Ra-, plays a critical role in both initiation and regulation of inflammation. However, the precise role of IL-1beta as a causative factor in IBD or simply a consequence of …

Abnormal Amygdala Subregion Functional Connectivity in Patients with Crohn's Disease with or without Anxiety and Depression

Publication Year: 2024 Source: Behav Neurol PMID: 38323301

No Abstract

Gut ribotoxic stress responses facilitate dyslipidemia via metabolic reprogramming: an environmental health prediction

Publication Year: 2024 Source: Theranostics PMID: 38323314

No Abstract

Microencapsulation as a Protective Strategy for Sialylated Immunoglobulin G: Efficacy in Alleviating Symptoms of Dextran Sulfate Sodium-Induced Colitis in Mice and Potential Mechanisms

Publication Year: 2024 Source: J Agric Food Chem PMID: 38323407 DOI: 10.1021/acs.jafc.3c07733

Sialylated immunoglobulin G (IgG) is a vital glycoprotein in breast milk with the ability to promote the growth of Bifidobacterium in gut microbiota and relieve inflammatory bowel disease (IBD) symptoms in vitro. Here, it was found that the microcapsules with sialylated IgG could protect and release sialylated IgG with its …

The New Frontiers of Gene Therapy and Gene Editing in Inflammatory Diseases

Publication Year: 2024 Source: Hum Gene Ther PMID: 38323580

No Abstract

Resveratrol-loaded pH-responsive Mesona chinensis polysaccharides-zein nanoparticles for effective treatment of ulcerative colitis

Publication Year: 2024 Source: J Sci Food Agric PMID: 38323719

No Abstract

Mediating effect of coping dispositions on the association between trauma and gastrointestinal symptoms

Publication Year: 2024 Source: Stress Health PMID: 38324223 DOI: 10.1002/smi.3380

Inflammatory bowel disease (IBD) and irritable bowel syndrome (IBS) are two gastrointestinal (GI) conditions known to be exacerbated by traumatic life experiences. One way in which these experiences might influence individuals' susceptibility to GI pathology, is by reducing their ability to deal with adversities effectively and predisposing them to passive …

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