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Meta-analysis: Persistence of advanced therapies in the treatment of inflammatory bowel disease
Publication Year: 2024 Source: Aliment Pharmacol Ther PMID: 38651771 DOI: 10.1111/apt.18006
BACKGROUND: The expanding options in advanced therapies for ulcerative colitis (UC) and Crohn's disease (CD) present challenges in treatment selection. Persistence analysis assesses drug durability in real-world settings, acting as a surrogate marker for medication efficacy and tolerance. Unlike traditional comparative studies, persistence analysis provides insights extending beyond the initial …
Recent steroid use and the relapse risk in ulcerative colitis patients with endoscopic healing
Publication Year: 2024 Source: Aliment Pharmacol Ther PMID: 38651779 DOI: 10.1111/apt.18013
BACKGROUND: Endoscopic healing (EH) is a therapeutic target in ulcerative colitis (UC). However, even patients who have achieved EH relapse frequently. AIMS: To investigate the association between recent steroid use and relapse risk in UC patients with EH. METHODS: This multi-centre cohort study included 1212 UC patients with confirmed EH …
Sarm1 Controls the MYD88-Mediated Inflammatory Responses in Inflammatory Bowel Disease via the Regulation of TRAF3 Recruitment
Publication Year: 2024 Source: Immunol Invest PMID: 38651786 DOI: 10.1080/08820139.2024.2343889
BACKGROUND: Sterile alpha and TIR motif-containing 1 (Sarm1) is known as a negative regulator of inflammatory responses. However, its role in inflammatory bowel disease (IBD) is still unclear. OBJECTIVE: This study aimed to explore the function of Sarm1 in IBD and its underlying mechanisms. Sarm1 and tumor necrosis factor (TNF) …
Reduction of product composition variability using pooled microbiome ecosystem therapy and consequence in two infectious murine models
Publication Year: 2024 Source: Appl Environ Microbiol PMID: 38651930
No Abstract
A randomized controlled trial of two hepatitis A vaccine doses among adolescents with juvenile idiopathic arthritis and Crohn's disease on immunosuppressive therapy: a pilot study
Publication Year: 2024 Source: J Travel Med PMID: 38652172
No Abstract
Reply to comments on: "Efficacy of cx601 (darvadstrocel) for the treatment of perianal fistulizing Crohn's disease-A prospective nationwide multicenter cohort study"
Publication Year: 2024 Source: Wien Klin Wochenschr PMID: 38652312
No Abstract
Intestinal ultrasound scan predicts corticosteroid failure and colectomy risk in patients with ulcerative colitis
Publication Year: 2024 Source: Eur J Gastroenterol Hepatol PMID: 38652524
No Abstract
Editorial: Is it time to include oral vancomycin in therapeutic guidelines for primary sclerosing cholangitis-associated inflammatory bowel disease?
Publication Year: 2024 Source: Aliment Pharmacol Ther PMID: 38652768
No Abstract
Editorial: Sequencing rescue therapy for acute severe ulcerative colitis-Ready for revision?
Publication Year: 2024 Source: Aliment Pharmacol Ther PMID: 38652770
No Abstract
Editorial: Sequencing rescue therapy for acute severe ulcerative colitis-Ready for revision? Authors' reply
Publication Year: 2024 Source: Aliment Pharmacol Ther PMID: 38652775
No Abstract
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