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Adenosine in Intestinal Epithelial Barrier Function
Publication Year: 2024 Source: Cells PMID: 38474346 DOI: 10.3390/cells13050381
At the intestinal front, several lines of defense are in place to resist infection and injury, the mucus layer, gut microbiome and strong epithelial junctions, to name a few. Their collaboration creates a resilient barrier. In intestinal disorders, such as inflammatory bowel disease (IBD), barrier function is compromised, which results …
Amygdalin Alleviates DSS-Induced Colitis by Restricting Cell Death and Inflammatory Response, Maintaining the Intestinal Barrier, and Modulating Intestinal Flora
Publication Year: 2024 Source: Cells PMID: 38474407 DOI: 10.3390/cells13050444
Inflammatory bowel disease (IBD) refers to a cluster of intractable gastrointestinal disorders with an undetermined etiology and a lack of effective therapeutic agents. Amygdalin (Amy) is a glycoside extracted from the seeds of apricot and other Rosaceae plants and it exhibits a wide range of pharmacological properties. Here, the effects …
Research Progress in Traditional Applications, Phytochemistry, Pharmacology, and Safety Evaluation of Cynomorium songaricum
Publication Year: 2024 Source: Molecules PMID: 38474452
No Abstract
Antimicrobial Activity of Syzygium aromaticum Essential Oil in Human Health Treatment
Publication Year: 2024 Source: Molecules PMID: 38474510
No Abstract
Lactate Protects Intestinal Epithelial Barrier Function from Dextran Sulfate Sodium-Induced Damage by GPR81 Signaling
Publication Year: 2024 Source: Nutrients PMID: 38474712
No Abstract
Heat-Killed Saccharomyces boulardii Alleviates Dextran Sulfate Sodium-Induced Ulcerative Colitis by Restoring the Intestinal Barrier, Reducing Inflammation, and Modulating the Gut Microbiota
Publication Year: 2024 Source: Nutrients PMID: 38474831
No Abstract
Preventing fibrosis in IBD: update on immune pathways and clinical strategies
Publication Year: 2024 Source: Expert Rev Clin Immunol PMID: 38475672 DOI: 10.1080/1744666X.2024.2330604
INTRODUCTION: Intestinal fibrosis is a common and serious complication of inflammatory bowel diseases (IBD) driving stricture formation in Crohn's disease patients and leading to submucosal damage in ulcerative colitis. Recent studies provided novel insights into the role of immune and nonimmune components in the pathogenesis of intestinal fibrosis. Those new …
Antidepressant fluoxetine alleviates colitis by reshaping intestinal microenvironment
Publication Year: 2024 Source: Cell Commun Signal PMID: 38475799 DOI: 10.1186/s12964-024-01538-5
BACKGROUND: The impact of antidepressants on Inflammatory bowel diseases (IBD) has been extensively studied. However, the biological effects and molecular mechanisms of antidepressants in alleviating colitis remain unclear. METHODS: We systematically assessed how antidepressants (fluoxetine, fluvoxamine and venlafaxine) affected IBD and chose fluoxetine, the most effective one, for mechanism studies. …
The evolving understanding of histology as an endpoint in ulcerative colitis
Publication Year: 2024 Source: Intest Res PMID: 38475998
No Abstract
Corrigendum: Poor prognostic factors of pharmacokinetic origin predict outcomes in inflammatory bowel disease patients treated with anti-tumor necrosis factor-α
Publication Year: 2024 Source: Front Immunol PMID: 38476224
No Abstract
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