Research Articles Library
Literature Analysis Tools
Advanced Search
Filter by PMID, year, source, DOI and other criteria
Literature Analysis
Analyze research trends and hotspots
Batch Export
Export search results to Excel/PDF
Poor prognostic factors of pharmacokinetic origin predict outcomes in inflammatory bowel disease patients treated with anti-tumor necrosis factor-α
Publication Year: 2024 Source: Front Immunol PMID: 38476237 DOI: 10.3389/fimmu.2024.1342477
INTRODUCTION: We evaluated baseline Clearance of anti-tumor necrosis factors and human leukocyte antigen variant (HLA DQA1*05) in combination as poor prognostic factors (PPF) of pharmacokinetic (PK) origin impacting immune response (formation of antidrug antibodies) and disease control of inflammatory bowel disease (IBD) patients treated with infliximab or adalimumab. METHODS: Baseline …
Association of Antidiabetic Drug Target Genes with Inflammatory Bowel Disease: A Mendelian Randomization Study
Publication Year: 2024 Source: J Inflamm Res PMID: 38476469 DOI: 10.2147/JIR.S441231
BACKGROUND: An unmet medical need for the treatment of inflammatory bowel disease (IBD) exists. A part of antidiabetic drugs had potential effects on IBD in various observational research. OBJECTIVE: To investigate the potential of antidiabetic drugs on IBD. METHODS: We undertook a summary-data-based Mendelian randomization (SMR) using the expression quantitative …
Anti-ulcerative colitis effects of chemically characterized extracts from Calliandra haematocephala in acetic acid-induced ulcerative colitis
Publication Year: 2024 Source: Front Chem PMID: 38476652
No Abstract
Effect of tofacitinib on the phenotype and activity of Caco‑2 cells in a model of inflammatory bowel disease
Publication Year: 2024 Source: Exp Ther Med PMID: 38476894 DOI: 10.3892/etm.2024.12440
Reports have indicated that autoimmune bowel disorders affect an increasing number of people on every continent; therefore, it is important to better understand inflammatory bowel disease (IBD) and to explore new treatment options for patients suffering from it. Research has indicated the important role of enterocytes in IBD. Understanding the …
Impact of COVID-19 on paediatric chronic intestinal failure: A tertiary care children's hospital experience
Publication Year: 2024 Source: J Pediatr Gastroenterol Nutr PMID: 38477361
No Abstract
Combination biologic therapy in pediatric inflammatory bowel disease: Safety and efficacy over a minimum 12-month follow-up period
Publication Year: 2024 Source: J Pediatr Gastroenterol Nutr PMID: 38477410 DOI: 10.1002/jpn3.12179
OBJECTIVES: The severe course of inflammatory bowel diseases (IBDs) refractory to advanced therapies in children results in the search for new therapeutic methods. The aim of this study was to evaluate the efficacy and safety of dual therapy with biologics in a cohort of children with IBD. METHODS: Retrospective analysis …
Gastrointestinal Dysmotility Predisposes to Colitis through Regulation of Gut Microbial Composition and Linoleic Acid Metabolism
Publication Year: 2024 Source: Adv Sci (Weinh) PMID: 38477534 DOI: 10.1002/advs.202306297
Disrupted gastrointestinal (GI) motility is highly prevalent in patients with inflammatory bowel disease (IBD), but its potential causative role remains unknown. Herein, the role and the mechanism of impaired GI motility in colitis pathogenesis are investigated. Increased colonic mucosal inflammation is found in patients with chronic constipation (CC). Mice with …
Iron therapy supplementation in inflammatory bowel disease patients with iron deficiency anemia: findings from a real-world analysis in Italy
Publication Year: 2024 Source: Eur J Gastroenterol Hepatol PMID: 38477856
No Abstract
Comparative maintenance performance of all biologic agents and small molecules in ulcerative colitis: a network meta-analysis
Publication Year: 2024 Source: Eur J Gastroenterol Hepatol PMID: 38477863
No Abstract
Attenuation of Colitis-Induced Visceral Hypersensitivity and Pain by Selective Silencing of TRPV1-Expressing Fibers in Rat Colon
Publication Year: 2024 Source: Inflamm Bowel Dis PMID: 38478397 DOI: 10.1093/ibd/izae036
BACKGROUND: Transient receptor potential vanilloid 1 (TRPV1) cation channels, expressed on nociceptors, are well established as key contributors to abdominal pain in inflammatory bowel disease (IBD). Previous attempts at blocking these channels have been riddled with side effects. Here, we propose a novel treatment strategy, utilizing the large pore of …
Need more literature?
The current database contains 98453 research articles. If you need to search for more literature or perform AI analysis, please use our knowledge acquisition module or explore external literature resources.
External Resources: Access comprehensive literature databases worldwide