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Gut bacteria-derived serotonin promotes immune tolerance in early life
Publication Year: 2024 Source: Sci Immunol PMID: 38489352
No Abstract
Contemporary perioperative outcomes after total abdominal colectomy for ulcerative colitis in a tertiary referral centre
Publication Year: 2024 Source: Eur J Gastroenterol Hepatol PMID: 38489595
No Abstract
Analysis of current situation and influencing factors of marital adjustment in patients with Crohn's disease and their spouses
Publication Year: 2024 Source: Medicine (Baltimore) PMID: 38489689
No Abstract
Fitness-for-use of Retrospective Multicenter Electronic Health Records to Conduct Outcome Analysis for Pediatric Ulcerative Colitis
Publication Year: 2024 Source: Medicine (Baltimore) PMID: 38489703
No Abstract
Potential effects and mechanism of flavonoids extract of Callicarpa nudiflora Hook on DSS-induced colitis in mice
Publication Year: 2024 Source: Phytomedicine PMID: 38489893
No Abstract
Integration of transcriptomics and metabolomics identify biomarkers of aberrant lipid metabolism in ulcerative colitis
Publication Year: 2024 Source: Int Immunopharmacol PMID: 38489972
No Abstract
Unleashing the Potential of Oral Deliverable Nanomedicine in the Treatment of Inflammatory Bowel Disease
Publication Year: 2024 Source: Cell Mol Gastroenterol Hepatol PMID: 38490294 DOI: 10.1016/j.jcmgh.2024.03.005
Inflammatory bowel disease (IBD), marked by chronic gastrointestinal tract inflammation, poses a significant global medical challenge. Current treatments for IBD, including corticosteroids, immunomodulators, and biologics, often require frequent systemic administration through parenteral delivery, leading to nonspecific drug distribution, suboptimal therapeutic outcomes, and adverse effects. There is a pressing need for …
Comprehensive Association Analyses of Extraintestinal Manifestations in Inflammatory Bowel Disease
Publication Year: 2024 Source: Gastroenterology PMID: 38490347 DOI: 10.1053/j.gastro.2024.02.026
BACKGROUND & AIMS: Patients with inflammatory bowel disease (IBD) frequently develop extraintestinal manifestations (EIMs) that contribute substantially to morbidity. We assembled the largest multicohort data set to date to investigate the clinical, serologic, and genetic factors associated with EIM complications in IBD. METHODS: Data were available in 12,083 unrelated European …
Sporisorium reilianum polysaccharides improve DSS-induced ulcerative colitis by regulating intestinal barrier function and metabolites
Publication Year: 2024 Source: Int J Biol Macromol PMID: 38490380
No Abstract
Gα12 and endoplasmic reticulum stress-mediated pyroptosis in a single cycle of dextran sulfate-induced mouse colitis
Publication Year: 2024 Source: Sci Rep PMID: 38491049 DOI: 10.1038/s41598-024-56685-z
Inflammatory bowel disease (IBD) pathogenesis involves complex inflammatory events and cell death. Although IBD involves mainly necrosis in the digestive tract, pyroptosis has also been recognized. Nonetheless, the underlying basis is elusive. Galpha12/13 overexpression may affect endoplasmic reticulum (ER) stress. This study examined how Galpha12/13 and ER stress affect pyroptosis …
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