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Notoginsenoside R1 promotes Lgr5(+) stem cell and epithelium renovation in colitis mice via activating Wnt/β-Catenin signaling
Publication Year: 2024 Source: Acta Pharmacol Sin PMID: 38491161 DOI: 10.1038/s41401-024-01250-7
Inflammatory bowel disease (IBD) is characterized by persistent damage to the intestinal barrier and excessive inflammation, leading to increased intestinal permeability. Current treatments of IBD primarily address inflammation, neglecting epithelial repair. Our previous study has reported the therapeutic potential of notoginsenoside R1 (NGR1), a characteristic saponin from the root of …
Does Combined Medical and Surgical Treatment Improve Perianal Fistula Outcomes in Patients With Crohn's Disease? A Systematic Review and Meta-Analysis
Publication Year: 2024 Source: J Crohns Colitis PMID: 38491943
No Abstract
JPEN Journal Club 83. Selecting trials to include in a systematic review
Publication Year: 2024 Source: JPEN J Parenter Enteral Nutr PMID: 38491963
No Abstract
Change in systemic steroid use and surgery rate in patients with inflammatory bowel disease: a Japanese real-world database analysis
Publication Year: 2024 Source: J Gastroenterol PMID: 38492011 DOI: 10.1007/s00535-024-02086-y
BACKGROUND: Corticosteroids are recommended only for induction of remission in inflammatory bowel disease (IBD), including ulcerative colitis (UC) and Crohn's disease (CD). This study aimed to evaluate the change in pharmacologic treatment use, particularly systemic corticosteroids, over approximately 30 years, and the impact of biologics on IBD treatment since their …
Resveratrol ameliorates DSS-induced ulcerative colitis by acting on mouse gut microbiota
Publication Year: 2024 Source: Inflammopharmacology PMID: 38492181
No Abstract
Tonic TCR and IL-1β signaling mediate phenotypic alterations of naive CD4(+) T cells
Publication Year: 2024 Source: Cell Rep PMID: 38492221
No Abstract
Protective effect of carbon dots as antioxidants on intestinal inflammation by regulating oxidative stress and gut microbiota in nematodes and mouse models
Publication Year: 2024 Source: Int Immunopharmacol PMID: 38492339 DOI: 10.1016/j.intimp.2024.111871
Inflammatory bowel disease (IBD) is a recurrent chronic colitis disease with increasing incidence and prevalence year by year. The single efficacy and significant side effects of traditional IBD treatment drugs have promoted the flourishing development of new drugs. Inspired by many health benefits of carbon dots (CDs) based nanomedicine in …
Exploration of gut microbiome and inflammation: A review on key signalling pathways
Publication Year: 2024 Source: Cell Signal PMID: 38492625
No Abstract
A hairy pedunculated polypoid lesion of sigmoid colon in a woman with abdominal pain and diarrhea
Publication Year: 2024 Source: Gastrointest Endosc PMID: 38492816
No Abstract
Upadacitinib Reduces Crohn's Disease Symptoms Within the First Week of Induction Therapy
Publication Year: 2024 Source: Clin Gastroenterol Hepatol PMID: 38492903
No Abstract
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