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An Update on the Role and Potential Molecules in Relation to Ruminococcus gnavus in Inflammatory Bowel Disease, Obesity and Diabetes Mellitus

Publication Year: 2024 Source: Diabetes Metab Syndr Obes PMID: 38496006 DOI: 10.2147/DMSO.S456173

Ruminococcus gnavus (R. gnavus) is a gram-positive anaerobe commonly resides in the human gut microbiota. The advent of metagenomics has linked R. gnavus with various diseases, including inflammatory bowel disease (IBD), obesity, and diabetes mellitus (DM), which has become a growing area of investigation. The initial focus of research primarily …

Self-adaptive pyroptosis-responsive nanoliposomes block pyroptosis in autoimmune inflammatory diseases

Publication Year: 2024 Source: Bioact Mater PMID: 38496034

No Abstract

Granulomas Galore: Concomitant Granulomatous Infections in a Patient With Crohn's Disease

Publication Year: 2024 Source: Cureus PMID: 38496097

No Abstract

A Narrative Review on the Viability of Osteopathic Manipulative Medicine in Treating Irritable Bowel Syndrome With Constipation (IBS-C)

Publication Year: 2024 Source: Cureus PMID: 38496183

No Abstract

Serine metabolism is crucial for cGAS-STING signaling and viral defense control in the gut

Publication Year: 2024 Source: iScience PMID: 38496294 DOI: 10.1016/j.isci.2024.109173

Inflammatory bowel diseases are characterized by the chronic relapsing inflammation of the gastrointestinal tract. While the molecular causality between endoplasmic reticulum (ER) stress and intestinal inflammation is widely accepted, the metabolic consequences of chronic ER stress on the pathophysiology of IBD remain unclear. By using in vitro, in vivo models, …

Integrated single-cell and bulk RNA sequencing reveals CREM is involved in the pathogenesis of ulcerative colitis

Publication Year: 2024 Source: Heliyon PMID: 38496850

No Abstract

The roles of ABCB1/P-glycoprotein drug transporters in regulating gut microbes and inflammation: insights from animal models, old and new

Publication Year: 2024 Source: Philos Trans R Soc Lond B Biol Sci PMID: 38497255 DOI: 10.1098/rstb.2023.0074

Commensal enteric bacteria have evolved systems that enable growth in the ecologic niche of the host gastrointestinal tract. Animals evolved parallel mechanisms to survive the constant exposure to bacteria and their metabolic by-products. We propose that drug transporters encompass a crucial system to managing the gut microbiome. Drug transporters are …

Integrated Metabolomics and Proteomics of Symptomatic and Early Presymptomatic States of Colitis

Publication Year: 2024 Source: J Proteome Res PMID: 38497760

No Abstract

[Primary sclerosing cholangitis-Diagnosis and treatment 2024]

Publication Year: 2024 Source: Inn Med (Heidelb) PMID: 38498179

No Abstract

Development of an Inflamed High Throughput Stem-cell-based Gut Epithelium Model to Assess the Impact of Annexin A1

Publication Year: 2024 Source: Stem Cell Rev Rep PMID: 38498294

No Abstract

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