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Is the use of secukinumab after anti-TNF therapy greater than expected for the risk of developing inflammatory bowel disease?
Publication Year: 2024 Source: Reumatol Clin (Engl Ed) PMID: 38494303 DOI: 10.1016/j.reumae.2023.11.002
OBJECTIVE: In this study, our objective was to present real-life data on the incidence of inflammatory bowel disease (IBD) among patients receiving secukinumab treatment. METHODS: The study consisted of 209 patients who had prior exposure to anti-tumor necrosis factor (TNF) or were biologically naive. Patients with a pre-existing history of …
Infantile inflammatory bowel disease in three Syrian infants: a case series
Publication Year: 2024 Source: J Med Case Rep PMID: 38494475 DOI: 10.1186/s13256-024-04456-9
BACKGROUND: Inflammatory bowel diseases, consisting of Crohn's disease and ulcerative colitis, are chronic bowel relapsing inflammatory disorders. Inflammatory bowel diseases begin rarely in infants. Approximately 25% of patients with inflammatory bowel diseases present before the age of 20 years. Very early-onset inflammatory bowel disease occurs before the age of 6 …
Promising clinical and immunological efficacy of Bacillus clausii spore probiotics for supportive treatment of persistent diarrhea in children
Publication Year: 2024 Source: Sci Rep PMID: 38494525
No Abstract
Characterizing identity by descent segments in Chinese interpopulation unrelated individual pairs
Publication Year: 2024 Source: Mol Genet Genomics PMID: 38494535 DOI: 10.1007/s00438-024-02132-7
Identity by descent (IBD) segments, uninterrupted DNA segments derived from the same ancestral chromosomes, are widely used as indicators of relationships in genetics. A great deal of research focuses on IBD segments between related pairs, while the statistical analyses of segments in irrelevant individuals are rare. In this study, we …
Linker-Based Pharmacophoric Design and Semisynthesis of Labdane Conjugates Active against Multi-Faceted Inflammatory Targets
Publication Year: 2024 Source: J Agric Food Chem PMID: 38494644
No Abstract
Large Yellow Tea Polysaccharide Alleviates HFD-Induced Intestinal Homeostasis Dysbiosis via Modulating Gut Barrier Integrity, Immune Responses, and the Gut Microbiome
Publication Year: 2024 Source: J Agric Food Chem PMID: 38494694
No Abstract
Efficacy and safety of filgotinib for ulcerative colitis: A real-world multicenter retrospective study in Japan
Publication Year: 2024 Source: Aliment Pharmacol Ther PMID: 38494867
No Abstract
Association between early life exposure to agriculture, biodiversity, and green space and risk of inflammatory bowel disease: a population-based cohort study
Publication Year: 2024 Source: EClinicalMedicine PMID: 38495524 DOI: 10.1016/j.eclinm.2024.102514
BACKGROUND: Specific pollutants and environmental exposures are implicated in modulating inflammatory bowel disease (IBD) risk. However, the role of environmental exposures, particularly during the early life period, towards IBD risk, has not been systematically evaluated. METHODS: We conducted a nationwide population-based cohort study during the study period extending from January …
Amoebic colitis-A diagnostic challenge on endoscopy: Case report
Publication Year: 2024 Source: SAGE Open Med Case Rep PMID: 38495736
No Abstract
Gut microbiota and its metabolites in Alzheimer's disease: from pathogenesis to treatment
Publication Year: 2024 Source: PeerJ PMID: 38495755
No Abstract
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