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Variation in the Care of Children with Inflammatory Bowel Disease Within and Across Canadian Provinces: A Multi-Province Population-Based Cohort Study

Publication Year: 2024 Source: Clin Epidemiol PMID: 38374886 DOI: 10.2147/CLEP.S449183

PURPOSE: The incidence of childhood-onset inflammatory bowel disease (IBD) is rising. We described variation in health services utilization and need for surgery among children with IBD between six and 60 months following IBD diagnosis across Canadian pediatric centers and evaluated the associations between care provided at diagnosis at each center …

Simultaneous onset of Crohn's disease and Psoriasis in a Multiple Sclerosis patient treated with Teriflunomide: A novel case report highlighting potential autoimmune interactions

Publication Year: 2024 Source: Heliyon PMID: 38375254 DOI: 10.1016/j.heliyon.2024.e26195

Teriflunomide (TFN) is an oral Disease-modifying therapy (DMT) widely used in the treatment of relapsing forms of Multiple Sclerosis (MS). Although TFN has demonstrated efficacy in reducing MS activity, recent evidence suggests a possible association between TFN and the onset of rare and severe medical conditions. We present a novel …

Does Surgery Before Pregnancy in Women With Inflammatory Bowel Disease Increase the Risk of Adverse Maternal and Fetal Outcomes? A Danish National Cohort Study

Publication Year: 2024 Source: Am J Gastroenterol PMID: 38376076

No Abstract

Is dependent cannabis use in adult hospitalizations with inflammatory bowel disease associated with major adverse cardiovascular and cerebrovascular events? Insights from National Inpatient Sample Analysis

Publication Year: 2024 Source: Curr Med Res Opin PMID: 38376123 DOI: 10.1080/03007995.2024.2321328

BACKGROUND: Inflammatory bowel disease (IBD) and dependent cannabis use or cannabis use disorder (CUD+) are independent risk factors for cardiovascular diseases. Usage of cannabis for pain increased in IBD patients. However, associated cardiovascular safety remains unclear. This study aims to investigate the major adverse cardiac and cerebrovascular events (MACCE) associated …

Mitochondrial-related genes PDK2, CHDH, and ALDH5A1 served as a diagnostic signature and correlated with immune cell infiltration in ulcerative colitis

Publication Year: 2024 Source: Aging (Albany NY) PMID: 38376420

No Abstract

Antibiotics for inflammatory bowel disease: Current status

Publication Year: 2024 Source: Indian J Gastroenterol PMID: 38376725 DOI: 10.1007/s12664-024-01537-x

There is abundant literature reporting about the use of antibiotics in inflammatory bowel disease (IBD), but their role in the management of IBD is not entirely clear. Diverse infectious organisms have been implicated in the pathogenesis of Crohn's disease. Also, infections are believed to be a trigger for flares of …

Concurrent Arterial and Venous Thromboses in Ulcerative Colitis: A Complex Case of Multiorgan Involvement

Publication Year: 2024 Source: Dig Dis Sci PMID: 38376786

No Abstract

Disseminated Mycobacterial Infection With Reactive Polyarthritis (Poncet's Disease) During Immune-suppressive Treatment Including Ustekinumab for Pediatric Crohn's Disease

Publication Year: 2024 Source: Pediatr Infect Dis J PMID: 38377462

No Abstract

Tauroursodeoxycholic acid liposome alleviates DSS-induced ulcerative colitis through restoring intestinal barrier and gut microbiota

Publication Year: 2024 Source: Colloids Surf B Biointerfaces PMID: 38377705

No Abstract

The gut microbiome regulates the clinical efficacy of sulfasalazine therapy for IBD-associated spondyloarthritis

Publication Year: 2024 Source: Cell Rep Med PMID: 38378002 DOI: 10.1016/j.xcrm.2024.101431

Sulfasalazine is a prodrug known to be effective for the treatment of inflammatory bowel disease (IBD)-associated peripheral spondyloarthritis (pSpA), but the mechanistic role for the gut microbiome in regulating its clinical efficacy is not well understood. Here, treatment of 22 IBD-pSpA subjects with sulfasalazine identifies clinical responders with a gut …

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