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The prophylaxis functions of Lactobacillus fermentum GLF-217 and Lactobacillus plantarum FLP-215 on ulcerative colitis via modulating gut microbiota of mice
Publication Year: 2024 Source: J Sci Food Agric PMID: 38406876
No Abstract
Risk of malignancy in a high-incidence population-based cohort of Faroese patients with inflammatory bowel disease from 1960 to 2020 - a Faroese IBD cohort study
Publication Year: 2024 Source: Scand J Gastroenterol PMID: 38407208 DOI: 10.1080/00365521.2024.2320712
BACKGROUND: The association between inflammatory bowel disease (IBD) and malignancy remains disputed despite many observational studies. The Faroese population exhibits the highest occurrence of IBD in the world. This study aimed to investigate the cancer risk in Faroese IBD patients in a nationwide IBD cohort. METHODS: This study included all …
Are Radiomic Spleen Features Useful for Assessing the Response to Infliximab in Patients With Crohn's Disease? A Multicenter Study
Publication Year: 2024 Source: Clin Transl Gastroenterol PMID: 38407213
No Abstract
Three-Dimensional Morphogenesis in Canine Gut-on-a-Chip Using Intestinal Organoids Derived from Inflammatory Bowel Disease Patients
Publication Year: 2024 Source: J Vis Exp PMID: 38407238 DOI: 10.3791/65720
Canine intestines possess similarities in anatomy, microbiology, and physiology to those of humans, and dogs naturally develop spontaneous intestinal disorders similar to humans. Overcoming the inherent limitation of three-dimensional (3D) organoids in accessing the apical surface of the intestinal epithelium has led to the generation of two-dimensional (2D) monolayer cultures, …
Active nanoparticle targeting of MUC5AC ameliorates therapeutic outcome in experimental colitis
Publication Year: 2024 Source: Nanoscale PMID: 38407269 DOI: 10.1039/d3nr05681c
Inflammatory bowel diseases (IBDs), which include Crohn's disease (CD) and ulcerative colitis (UC), are chronic inflammatory diseases of the gastrointestinal tract and are characterized by chronic recurrent ulceration of the bowels. Colon-targeted drug delivery systems (DDS) have received significant attention for their potential to treat IBD by improving the inflamed …
Modern practical management of acute severe colitis
Publication Year: 2024 Source: Indian J Gastroenterol PMID: 38407787 DOI: 10.1007/s12664-024-01522-4
Acute severe ulcerative colitis (ASUC) is one of life-threatening complications that occur in one-fifth of ulcerative colitis (UC) patients with significant morbidity and an estimated mortality rate up to 1%. There are no validated clinical scoring systems for ASUC. Intravenous corticosteroids remain the cornerstone for the management of ASUC patients …
Inflammatory bowel disease is associated with multiple sclerosis or Hodgkin lymphoma
Publication Year: 2024 Source: Eur J Gastroenterol Hepatol PMID: 38407888
No Abstract
Comparative effectiveness and safety of ustekinumab at different intervals of maintenance phase in inflammatory bowel disease: a systematic review and meta-analysis
Publication Year: 2024 Source: Eur J Gastroenterol Hepatol PMID: 38407891 DOI: 10.1097/MEG.0000000000002718
Ustekinumab has two alternative drug maintenance intervals for inflammatory bowel disease (IBD), every 8 weeks (Q8W) and every 12 weeks (Q12W). The current study aimed at evaluating the comparative efficacy and safety of the two maintenance intervals in patients with IBD. A systematic search on PubMed, Web of Science, Cochrane …
Osteonecrosis in patients with inflammatory bowel disease: a systematic review and meta-analysis
Publication Year: 2024 Source: Eur J Gastroenterol Hepatol PMID: 38407895 DOI: 10.1097/MEG.0000000000002735
BACKGROUND: The relationship of inflammatory bowel disease (IBD) with osteonecrosis or avascular necrosis (AVN) is uncertain. METHODS: Systematic review to estimate the frequency of osteonecrosis in IBD was performed. Electronic databases were searched on 12 December 2022 to identify relevant studies. We planned to estimate the pooled prevalence of AVN …
The Epidemiology of Inflammatory Bowel Diseases During the COVID-19 Pandemic: Comparison of Two Nationwide Cohorts
Publication Year: 2024 Source: J Crohns Colitis PMID: 38407990 DOI: 10.1093/ecco-jcc/jjae029
BACKGROUND: We aimed to explore the epidemiology of inflammatory bowel diseases [IBD] in association with the COVID-19 pandemic in two countries with different lockdown policies. METHODS: We utilized nationwide IBD cohorts in Israel and Sweden to explore the incidence of IBD during the pandemic compared to 3 years prior [2017-2019]. …
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