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Short noncoding RNAs as predictive biomarkers for the development from inflammatory bowel disease unclassified to Crohn's disease or ulcerative colitis
Publication Year: 2024 Source: PLoS One PMID: 38408066 DOI: 10.1371/journal.pone.0297353
Numerous pathogenic processes are mediated by short noncoding RNAs (sncRNA). Twenty percent of inflammatory bowel disease (IBD) patients are labelled as IBD unclassified (IBDU) at disease onset. Most IBDU patients are reclassified as Crohn's disease (CD) or ulcerative colitis (UC) within few years. Since the therapeutic methods for CD and …
Causal Association Analysis of Periodontitis and Inflammatory Bowel Disease: A Bidirectional Mendelian Randomization Study
Publication Year: 2024 Source: Inflamm Bowel Dis PMID: 38408068 DOI: 10.1093/ibd/izad188
BACKGROUND: Periodontitis has been reported to be associated with inflammatory bowel disease (IBD), including ulcerative colitis (UC), and Crohn's disease (CD). However, the causality of these 2 diseases remains unclear. We conducted bidirectional Mendelian randomization (MR) to investigate the causal relationship between periodontitis and IBD. METHODS: We obtained the genome-wide …
Clinical Outcomes at 8-16 Weeks After Upadacitinib Initiation for Acute Severe Ulcerative Colitis: A Case Series in the United States
Publication Year: 2024 Source: Inflamm Bowel Dis PMID: 38408096
No Abstract
Autologous stem cell transplantation with low-dose cyclophosphamide to improve mucosal healing in adults with refractory Crohn’s disease: the ASTIClite RCT
Publication Year: 2024 Source: Autologous stem cell transplantation with low-dose cyclophosphamide to improve mucosal healing in adults with refractory Crohn’s disease: the ASTIClite RCT PMID: 38408175
No Abstract
Outcomes in Adult Inflammatory Bowel Disease Clinical Trials: Assessment of Similarity Among Participants with Adolescent-onset and Adult-onset Disease
Publication Year: 2024 Source: J Crohns Colitis PMID: 38408273 DOI: 10.1093/ecco-jcc/jjae030
BACKGROUND AND AIMS: Most paediatric inflammatory bowel disease [IBD] studies are performed after medications are approved in adults, and the majority of participants in these studies are adolescents. We hypothesised that adolescent-onset IBD is not fundamentally different from adult-onset IBD. If this is correct, the value of delaying access to …
Intestinal stroma guides monocyte differentiation to macrophages through GM-CSF
Publication Year: 2024 Source: Nat Commun PMID: 38409190 DOI: 10.1038/s41467-024-46076-3
Stromal cells support epithelial cell and immune cell homeostasis and play an important role in inflammatory bowel disease (IBD) pathogenesis. Here, we quantify the stromal response to inflammation in pediatric IBD and reveal subset-specific inflammatory responses across colon segments and intestinal layers. Using data from a murine dynamic gut injury …
High-resolution rectoscopy using MHz optical coherence tomography: a step towards real time 3D endoscopy
Publication Year: 2024 Source: Sci Rep PMID: 38409328
No Abstract
A comprehensive guide to assess gut mycobiome and its role in pathogenesis and treatment of inflammatory bowel disease
Publication Year: 2024 Source: Indian J Gastroenterol PMID: 38409485 DOI: 10.1007/s12664-023-01510-0
Inflammatory bowel disease (IBD) is an immune mediated chronic inflammatory disorder of gastrointestinal tract, which has underlying multifactorial pathogenic determinants such as environmental factors, susceptibility genes, gut microbial dysbiosis and a dysregulated immune response. Human gut is a frequent inhabitant of complex microbial ecosystem encompassing bacteria, viruses, parasites, fungi and …
Effect of cannabinoids in mild-to-moderate cases of Crohn's disease as compared to placebo: a systematic review and meta-analysis of randomised controlled trials
Publication Year: 2024 Source: J Basic Clin Physiol Pharmacol PMID: 38409768
No Abstract
Jejunovesical Fistula Diagnosis After Normal Vaginal Delivery: A Case Report
Publication Year: 2024 Source: JNMA J Nepal Med Assoc PMID: 38410006
No Abstract
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