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Our Life Is a Rollercoaster! A Qualitative Phenomenological Study Exploring the Impact of IBD on Family Members
Publication Year: 2024 Source: Inflamm Bowel Dis PMID: 38417051 DOI: 10.1093/ibd/izae028
BACKGROUND: Inflammatory bowel disease (IBD) significantly impacts patients and their families. To provide support, understanding the effects on the wider family is crucial. However, limited research exists on the impact of IBD on family members of adults diagnosed with IBD. This study addresses this knowledge gap. METHODS: Underpinned by interpretive …
Efficacy of vedolizumab during intravenous induction therapy in ulcerative colitis and Crohn's disease: post hoc analysis of patient-reported outcomes from the VISIBLE 1 and 2 studies
Publication Year: 2024 Source: Eur J Gastroenterol Hepatol PMID: 38417060
No Abstract
Unravelling the Oral-Gut Axis: Interconnection Between Periodontitis and Inflammatory Bowel Disease, Current Challenges, and Future Perspective
Publication Year: 2024 Source: J Crohns Colitis PMID: 38417137 DOI: 10.1093/ecco-jcc/jjae028
As the opposite ends of the orodigestive tract, the oral cavity and the intestine share anatomical, microbial, and immunological ties that have bidirectional health implications. A growing body of evidence suggests an interconnection between oral pathologies and inflammatory bowel disease [IBD], implying a shift from the traditional concept of independent …
Characteristics and Prognosis of Sporadic Neoplasias Detected in Patients with Ulcerative Colitis
Publication Year: 2024 Source: Digestion PMID: 38417416
No Abstract
pH-responsive CuS/DSF/EL/PVP nanoplatform alleviates inflammatory bowel disease in mice via regulating gut immunity and microbiota
Publication Year: 2024 Source: Acta Biomater PMID: 38417643 DOI: 10.1016/j.actbio.2024.02.034
The clinical treatment of inflammatory bowel disease (IBD) is challenging. We developed copper sulfate (CuS)/disulfiram (DSF)/methacrylic acid-ethyl acrylate copolymer (EL)/polyvinylpyrrolidone (PVP) nanoplatform (CuS/DSF/EL/PVP) and evaluated its efficiency for treating IBD. After oral administration, the pH-sensitive EL protected the CuS/DSF/EL/PVP against degradation by acidic gastric juices. Once the colon was reached, …
Heterogeneity of mesenchymal stem cells as a limiting factor in their clinical application to inflammatory bowel disease in dogs and cats
Publication Year: 2024 Source: Vet J PMID: 38417670 DOI: 10.1016/j.tvjl.2024.106090
Inflammatory bowel disease (IBD) is a major subtype of chronic enteropathies in dogs and cats. Conventional drugs such as immunomodulatory medicines as glucocorticoids and/or other anti-inflammatory are mainly applied for treatment. However, these drugs are not always effective to maintain remission from IBD and are limited by unacceptable side effects. …
Serine Supports Epithelial and Immune Cell Function in Colitis
Publication Year: 2024 Source: Am J Pathol PMID: 38417696 DOI: 10.1016/j.ajpath.2024.01.021
Inflammatory bowel diseases (IBD) are chronic inflammatory disorders of the gastrointestinal tract that are largely driven by immune cell activity, and mucosal healing is critical for remission. Serine is a nonessential amino acid that supports epithelial and immune cell metabolism and proliferation; however, whether these roles affect IBD pathogenesis is …
ORMDL3 regulates NLRP3 inflammasome activation by maintaining ER-mitochondria contacts in human macrophages and dictates ulcerative colitis patient outcome
Publication Year: 2024 Source: J Biol Chem PMID: 38417794
No Abstract
[Takayasu arteritis after COVID-19 infection in a 26-year-old female patient with Crohn's disease]
Publication Year: 2024 Source: Z Gastroenterol PMID: 38417807
No Abstract
Mercaptopurine-induced Sweet's syndrome
Publication Year: 2024 Source: BMJ Case Rep PMID: 38417937
No Abstract
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