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Common gastrointestinal symptoms and their impact on psychological state and quality of life in patients with inflammatory bowel disease: a cross-sectional multicenter study in China

Publication Year: 2024 Source: Gastroenterol Rep (Oxf) PMID: 38586540 DOI: 10.1093/gastro/goae019

OBJECTIVE: To explore the impact of common gastrointestinal (GI) symptoms on psychological symptoms, sleep quality, and quality of life in patients with inflammatory bowel disease (IBD). METHODS: A unified questionnaire was developed to collect clinical data on the mental psychology and quality of life of IBD patients from 42 hospitals …

Very Early Onset of Fistulizing Inflammatory Bowel Disease With RIPK1 Mutation: A Case Report

Publication Year: 2024 Source: Cureus PMID: 38586767 DOI: 10.7759/cureus.55708

Infantile inflammatory bowel disease (IBD) is a very rare subgroup of IBD that develops in children younger than two years with genetic susceptibility, especially in those with monogenic defects. This type, when compared with IBD in older children, is more resistant to conventional medical treatment and presents with more complications …

Atypical Presentation of Retroperitoneal Fibrosis Causing Colonic Obstruction: A Case Report

Publication Year: 2024 Source: Cureus PMID: 38586788

No Abstract

A Retrospective Observational Study of Patterns of Biologic Drug Change in Inflammatory Bowel Disease

Publication Year: 2024 Source: Inflamm Intest Dis PMID: 38586860 DOI: 10.1159/000538250

INTRODUCTION: Multiple therapies are currently available for inflammatory bowel disease (IBD); it is therefore crucial to understand patterns of drug change. This study aimed to examine the patterns of biological drug change and identify predictors of change in patients with IBD. METHODS: We performed a retrospective study of patients diagnosed …

Real-world clinical outcomes and healthcare costs in patients with Crohn's disease treated with vedolizumab versus ustekinumab in the United States

Publication Year: 2024 Source: Curr Med Res Opin PMID: 38586979

No Abstract

Therapeutic drug monitoring in patients with inflammatory bowel disease on ustekinumab

Publication Year: 2024 Source: J Dig Dis PMID: 38587053 DOI: 10.1111/1751-2980.13264

OBJECTIVE: Therapeutic drug monitoring is used clinically to guide anti-tumor necrosis factor (TNF) therapy for inflammatory bowel disease (IBD), but its use for ustekinumab (UST) remains unclear. This study aimed to determine predictive variables of UST levels. METHODS: In this retrospective cohort of patients with IBD, UST trough levels were …

Ocular endothelial dysfunction in pediatric inflammatory bowel disease

Publication Year: 2024 Source: J Pediatr Gastroenterol Nutr PMID: 38587115 DOI: 10.1002/jpn3.12208

OBJECTIVES: To assess ocular microvasculature changes using optical coherence tomography angiography (OCTA) in pediatric patients with inflammatory bowel disease (IBD). METHODS: Patients (aged 6-18 years) with IBD were recruited between September 2021 and May 2023. All eligible participants underwent comprehensive clinical assessment and laboratory investigation. Patients with functional gastrointestinal disorders …

Consistent efficacy outcomes between phase 2 and phase 3 trials in Crohn's disease or ulcerative colitis in adults: a meta-analysis

Publication Year: 2024 Source: Inflamm Res PMID: 38587530

No Abstract

Gene expression alterations of purinergic signaling components in obesity-associated intestinal low-grade inflammation in type 2 diabetes

Publication Year: 2024 Source: Purinergic Signal PMID: 38587723

No Abstract

Ustekinumab Offers Long-Term Clinical Remission With Safety in Very Early-Onset Inflammatory Bowel Disease

Publication Year: 2024 Source: Inflamm Bowel Dis PMID: 38588461

No Abstract

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