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Accumulated LPS induced by colitis altered the activities of vitamin D-metabolizing hydroxylases and decreased the generation of 25-hydroxyvitamin D
Publication Year: 2024 Source: Chem Biol Interact PMID: 38588969 DOI: 10.1016/j.cbi.2024.110997
It is generally accepted that low vitamin D (VD) levels are associated with a high prevalence factor for Inflammatory bowel disease (IBD). IBD patients have observed higher levels of lipopolysaccharide (LPS), ALT, and AST than healthy people. Gut-derived LPS causes inflammatory injury in the liver and kidney. The VD-metabolizing mechanism …
Myelin oligodendrocyte glycoprotein antibody-associated disease presenting as unilateral cerebral cortical encephalitis: a case report
Publication Year: 2024 Source: Encephalitis PMID: 38589019
No Abstract
"TB - Mindedness"-the only way to beat "the great mimicker": A case series with atypical presentation of female genital tuberculosis
Publication Year: 2024 Source: Indian J Tuberc PMID: 38589122 DOI: 10.1016/j.ijtb.2023.04.027
BACKGROUND: Incidence of Tuberculosis (TB) cases in India reported in 2019 is 193 per 1 lakh population [National Tuberculosis Elimination Plan (NTEP)]. In India, annual extra pulmonary TB burden is 20-25%, of which 4% of cases are of urogenital origin (Revised National TB Control Programme, 2019; World Health Organization, 2019). …
Real-world NUDT15 genotyping and thiopurine treatment optimization in inflammatory bowel disease: a multicenter study
Publication Year: 2024 Source: J Gastroenterol PMID: 38589597 DOI: 10.1007/s00535-024-02099-7
BACKGROUND: This study evaluated the effectiveness of NUDT15 codon 139 genotyping in optimizing thiopurine treatment for inflammatory bowel disease (IBD) in Japan, using real-world data, and aimed to establish genotype-based treatment strategies. METHODS: A retrospective analysis of 4628 IBD patients who underwent NUDT15 codon 139 genotyping was conducted. This study …
Anti-tumor necrosis factor-α therapy may not be safe during pregnancy in women with inflammatory bowel disease: an updated meta-analysis and systematic review
Publication Year: 2024 Source: BMC Pregnancy Childbirth PMID: 38589784 DOI: 10.1186/s12884-024-06443-w
BACKGROUND: Inflammatory Bowel Disease (IBD) affects reproductive-aged women. Active disease can lead to decreased fertility. Although the vast majority of international guidelines recommend for the continuation of anti-TNF-alpha during pregnancy, recent studies have raised concerns about the safety of anti-tumor necrosis factor-alpha (TNF-alpha) therapy during pregnancy, both for patients and …
Methods of determining optimal cut-point of diagnostic biomarkers with application of clinical data in ROC analysis: an update review
Publication Year: 2024 Source: BMC Med Res Methodol PMID: 38589814 DOI: 10.1186/s12874-024-02198-2
INTRODUCTION: An important application of ROC analysis is the determination of the optimal cut-point for biomarkers in diagnostic studies. This comprehensive review provides a framework of cut-point election for biomarkers in diagnostic medicine. METHODS: Several methods were proposed for the selection of optional cut-points. The validity and precision of the …
An artificial intelligence-driven scoring system to measure histological disease activity in ulcerative colitis
Publication Year: 2024 Source: United European Gastroenterol J PMID: 38590110
No Abstract
Review article: A practical approach to persistent gastrointestinal symptoms in inflammatory bowel disease in remission
Publication Year: 2024 Source: Aliment Pharmacol Ther PMID: 38590140 DOI: 10.1111/apt.17988
BACKGROUND: Persistent gastrointestinal symptoms are prevalent in adult patients with inflammatory bowel disease (IBD), even when endoscopic remission is reached. These symptoms can have profound negative effects on the quality of life of affected patients and can be difficult to treat. They may be caused by IBD-related complications or comorbid …
Intravenous iron-induced hypophosphatemia and kidney stone disease
Publication Year: 2024 Source: Bone Rep PMID: 38590391
No Abstract
Concomitant Cytomegalovirus Viraemia in Multisystem Inflammatory Syndrome in Adults (MIS-A) following COVID-19
Publication Year: 2024 Source: Case Rep Infect Dis PMID: 38590710
No Abstract
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