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Impact of sex and socioeconomic status on the likelihood of surgery, hospitalization, and use of medications in inflammatory bowel disease: a systematic review and meta-analysis
Publication Year: 2024 Source: Syst Rev PMID: 38915086 DOI: 10.1186/s13643-024-02584-3
BACKGROUND: Inflammatory bowel diseases (IBDs) are associated with high healthcare utilization. This systematic review aimed to summarize what is known about the impact of sex, income, and education on the likelihood of bowel surgery, hospitalization, and use of corticosteroids and biologics among patients with IBD. METHODS: We used EMBASE, MEDLINE, …
Stratifying macrophages based on their infectious burden identifies novel host targets for intervention during Crohn's disease associated adherent-invasive Escherichia coli infection
Publication Year: 2024 Source: Microbiology (Reading) PMID: 38916198
No Abstract
Gastroenterology healthcare in LGBTQ+ individuals
Publication Year: 2024 Source: Eur J Gastroenterol Hepatol PMID: 38916210
No Abstract
A Population-Based Matched Cohort Study of Digestive System Cancer Incidence and Mortality in Individuals With and Without Inflammatory Bowel Disease
Publication Year: 2024 Source: Am J Gastroenterol PMID: 38916226 DOI: 10.14309/ajg.0000000000002900
No Abstract
Development of a set of measurable outcome indicators for Flemish patients with inflammatory bowel disease
Publication Year: 2024 Source: Eur J Gastroenterol Hepatol PMID: 38916231 DOI: 10.1097/MEG.0000000000002804
OBJECTIVE: Uniform and standardised quality measurement allows care assessment and improvement. Following a pragmatic consensus method we aimed to agree on a selection of measurable quality indicators that can be used to assess, benchmark and gradually improve inflammatory bowel disease (IBD) care in Flanders. METHODS: Of 49 structures, 135 processes …
Updated evidence of the effectiveness and safety of transanal drainage tube for the prevention of anastomotic leakage after rectal low anterior resection: a systematic review and meta-analysis
Publication Year: 2024 Source: Tech Coloproctol PMID: 38916755
No Abstract
The epithelial C15ORF48/miR-147-NDUFA4 axis is an essential regulator of gut inflammation, energy metabolism, and the microbiome
Publication Year: 2024 Source: Proc Natl Acad Sci U S A PMID: 38917002 DOI: 10.1073/pnas.2315944121
Chronic inflammation is epidemiologically linked to the pathogenesis of gastrointestinal diseases, including inflammatory bowel disease (IBD) and colorectal cancer (CRC). However, our understanding of the molecular mechanisms controlling gut inflammation remains insufficient, hindering the development of targeted therapies for IBD and CRC. In this study, we uncovered C15ORF48/miR-147 as a …
Repurposing metformin as adjuvant therapy in patients with ulcerative colitis treated with mesalamine: A randomized controlled double-blinded study
Publication Year: 2024 Source: Int Immunopharmacol PMID: 38917525
No Abstract
Discovery of disease-adapted bacterial lineages in inflammatory bowel diseases
Publication Year: 2024 Source: Cell Host Microbe PMID: 38917808 DOI: 10.1016/j.chom.2024.05.022
Gut bacteria are implicated in inflammatory bowel disease (IBD), but the strains driving these associations are unknown. Large-scale studies of microbiome evolution could reveal the imprint of disease on gut bacteria, thus pinpointing the strains and genes that may underlie inflammation. Here, we use stool metagenomes of thousands of IBD …
[Risks of Cancer Associated with Therapeutic Drugs for Inflammatory Bowel Disease]
Publication Year: 2024 Source: Korean J Gastroenterol PMID: 38918036 DOI: 10.4166/kjg.2024.053
Crohn's disease and ulcerative colitis are lifelong chronic inflammatory conditions, with many patients requiring ongoing immunomodulatory drug therapy for maintenance treatment. Recent therapeutic goals in inflammatory bowel disease (IBD) are not only aimed at symptomatic remission but also at achieving mucosal healing to improve the natural course of the disease. …
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