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Targeting the intestinal circadian clock by meal timing ameliorates gastrointestinal inflammation
Publication Year: 2024 Source: Cell Mol Immunol PMID: 38918576 DOI: 10.1038/s41423-024-01189-z
The expression of clock genes has been observed to be impaired in biopsies from patients with inflammatory bowel disease (IBD). Disruption of circadian rhythms, which occurs in shift workers, has been linked to an increased risk of gastrointestinal diseases, including IBD. The peripheral circadian clock in intestinal epithelial cells (IECs) …
Investigation of TLR2 (-196 to -174del) and TLR9 (T-1486C) Gene Polymorphisms Association with Inflammatory Bowel Diseases
Publication Year: 2024 Source: Asian Pac J Cancer Prev PMID: 38918662 DOI: 10.31557/APJCP.2024.25.6.2003
BACKGROUND: Inflammatory bowel diseases (IBD), Crohn's disease (CD), and ulcerative colitis (UC) are diseases that result from the combined effects of a predisposing genetic background and several environmental factors, including smoking. Some genes can influence these diseases through genetic inheritance, and their regulation is explained by gene polymorphism. However, Toll-like …
Risk factors for endoscopic postoperative recurrence in patients with Crohn's Disease: a protocol for systematic review and meta-analysis
Publication Year: 2024 Source: BMC Gastroenterol PMID: 38918740
No Abstract
Breaking barriers: bacterial-microalgae symbiotic systems as a probiotic delivery system
Publication Year: 2024 Source: J Nanobiotechnology PMID: 38918805 DOI: 10.1186/s12951-024-02647-6
The gut microbiota is one of the essential contributors of the pathogenesis and progress of inflammatory bowel disease (IBD). Compared with first-line drug therapy, probiotic supplementation has emerged as a viable and secure therapeutic approach for managing IBD through the regulation of both the immune system and gut microbiota. Nevertheless, …
Phytochemicals: a promising approach to control infectious bursal disease
Publication Year: 2024 Source: Front Vet Sci PMID: 38919155 DOI: 10.3389/fvets.2024.1421668
Infectious bursal disease (IBD) is one of the dangerous diseases of poultry that affects the bursa of Fabricius, which is an important organ of the bird's immune system. IBD virus is resistant to many drugs, making its control difficult. Vaccination of IBD is in practice for a long time worldwide …
Case report: The success of empagliflozin therapy for glycogen storage disease type 1b
Publication Year: 2024 Source: Front Endocrinol (Lausanne) PMID: 38919482 DOI: 10.3389/fendo.2024.1365700
INTRODUCTION: Glycogen storage disease type 1b (GSD-1b) is characterized by neutropenia and neutrophil dysfunction generated by the accumulation of 1,5-anhydroglucitol-6-phosphate in neutrophils. Sodium-glucose co-transporter 2 inhibitors, such as empagliflozin, facilitate the removal of this toxic metabolite and ameliorate neutropenia-related symptoms, including severe infections and inflammatory bowel disease (IBD). Our case …
Unraveling the propensity of various genetic disorders and syndromes in the Koraga, an aboriginal tribe from southern India
Publication Year: 2024 Source: J Biosci PMID: 38920107
Koragas, recognized as a particularly vulnerable tribal group (PVTG) by the Government of India, are from coastal Karnataka and Kerala. They are experiencing severe socioeconomic and health-related issues and rapid depopulation. The unique genetic makeup of Koragas has been maintained by the practice of endogamy. We aimed to identify genetic …
Fecal and Serum Granulocyte Protein Levels in Inflammatory Bowel Disease and Irritable Bowel Syndrome and Their Relation to Disease Activity
Publication Year: 2024 Source: Clin Transl Gastroenterol PMID: 38920307 DOI: 10.14309/ctg.0000000000000733
INTRODUCTION: Neutrophilic calprotectin (CP) and myeloperoxidase (MPO), neutrophil gelatinase-associated lipocalin (NGAL), and eosinophil-derived neurotoxin (EDN) are suggested proxy markers for gut inflammation. However, there are insufficient supporting data for MPO, NGAL, and EDN. METHODS: In a cross-sectional investigation including adult patients, we studied the ability of CP, MPO, NGAL, and …
Mindfulness, Gut-Brain Axis, and Health-Related Quality of Life: The Paradigm of IBD Patients
Publication Year: 2024 Source: Healthcare (Basel) PMID: 38921323 DOI: 10.3390/healthcare12121209
Health-related quality of life (HRQoL) is a comprehensive measure that evaluates an individual's well-being across physical, mental, and social dimensions. Enhancing HRQoL, particularly in individuals with chronic conditions like inflammatory bowel diseases (IBD), necessitates a holistic approach. Mindfulness, a scientifically supported strategy for managing anxiety, has shown promise in improving …
Motivational Interviewing as a Strategy to Improve Adherence in IBD Treatment: An Integrative Review Amidst COVID-19 Disruptions
Publication Year: 2024 Source: Healthcare (Basel) PMID: 38921325 DOI: 10.3390/healthcare12121210
Aims and Objectives: This review aims to analyze the effectiveness of motivational interviewing (MI) in enhancing therapeutic adherence and compliance in adult patients with inflammatory bowel disease (IBD), especially considering the disruptions caused by the COVID-19 pandemic. Background: IBD, which includes conditions such as ulcerative colitis and Crohn's disease, affects …
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