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Early Growth Response Protein 1 Exacerbates Murine Inflammatory Bowel Disease by Transcriptional Activation of Matrix Metalloproteinase 12

Publication Year: 2024 Source: Biomedicines PMID: 38672136 DOI: 10.3390/biomedicines12040780

Inflammatory bowel disease (IBD) is an inflammatory condition affecting the colon and small intestine, with Crohn's disease and ulcerative colitis being the major types. Individuals with long-term IBD are at an increased risk of developing colorectal cancer. Early growth response protein 1 (Egr1) is a nuclear protein that functions as …

Exploring the Potential of Humoral Immune Response to Commensal Bifidobacterium as a Biomarker for Human Health, including Both Malignant and Non-Malignant Diseases: A Perspective on Detection Strategies and Future Directions

Publication Year: 2024 Source: Biomedicines PMID: 38672158

No Abstract

Therapeutic Drug Monitoring as a Tool for the Clinical Outcome Prediction in Vedolizumab-Treated Patients: An Italian Pilot Study

Publication Year: 2024 Source: Biomedicines PMID: 38672179 DOI: 10.3390/biomedicines12040824

Over the years, vedolizumab (VDZ) has emerged as a more effective target therapy for inflammatory bowel disease. The aim of this work was to analyze a cohort of inflammatory bowel disease patients, evaluating the association between VDZ serum concentrations at 6 months from starting therapy and their clinical and biochemical …

Inflammation and Organic Cation Transporters Novel (OCTNs)

Publication Year: 2024 Source: Biomolecules PMID: 38672410

No Abstract

Krill Oil and Its Bioactive Components as a Potential Therapy for Inflammatory Bowel Disease: Insights from In Vivo and In Vitro Studies

Publication Year: 2024 Source: Biomolecules PMID: 38672464 DOI: 10.3390/biom14040447

Krill oil is extracted from krill, a small crustacean in the Antarctic Ocean. It has received growing attention because of krill oil's unique properties and diverse health benefits. Recent experimental and clinical studies suggest that it has potential therapeutic benefits in preventing the development of a range of chronic conditions, …

Impact of COVID-19 on Pediatric Inflammatory Bowel Diseases-From Expectations to Reality

Publication Year: 2024 Source: J Pers Med PMID: 38673026 DOI: 10.3390/jpm14040399

Viral infections have always been considered a threat to global health, with numerous outbreaks across time. Despite the relative recent experience with coronavirus-associated diseases such as severe acute respiratory syndrome (SARS) and Middle East respiratory syndrome (MERS), severe acute respiratory syndrome-2's (SARS-CoV-2) continuous evolution displays a different behavior. With a …

Physical Activity Levels and Social Cognitive Theory Correlates among Adults with Crohn's Disease: Preliminary Results from a Cross-Sectional Analysis

Publication Year: 2024 Source: Int J Environ Res Public Health PMID: 38673373

No Abstract

Ustekinumab or Vedolizumab after Failure of Anti-TNF Agents in Crohn's Disease: A Review of Comparative Effectiveness Studies

Publication Year: 2024 Source: J Clin Med PMID: 38673459

No Abstract

Dysbiosis in Inflammatory Bowel Disease and Spondyloarthritis: Still a Long Way to Go?

Publication Year: 2024 Source: J Clin Med PMID: 38673510 DOI: 10.3390/jcm13082237

The association between Inflammatory Bowel Disease (IBD) and Spondyloarthritis (SpA) has been known for years, as has the concept that IBD is associated with an altered intestinal bacterial composition, a condition known as "dysbiosis". Recently, a state of intestinal dysbiosis has also been found in SpA. Dysbiosis in the field …

Management of Post-Operative Crohn's Disease: Knowns and Unknowns

Publication Year: 2024 Source: J Clin Med PMID: 38673573

No Abstract

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