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The Complex Relationship between Mechanisms Underlying Inflammatory Bowel Disease, Its Treatment, and the Risk of Lymphomas: A Comprehensive Review
Publication Year: 2024 Source: Int J Mol Sci PMID: 38673824
No Abstract
Myeloperoxidase Gene Deletion Causes Drastic Microbiome Shifts in Mice and Does Not Mitigate Dextran Sodium Sulphate-Induced Colitis
Publication Year: 2024 Source: Int J Mol Sci PMID: 38673843 DOI: 10.3390/ijms25084258
Neutrophil-myeloperoxidase (MPO) is a heme-containing peroxidase which produces excess amounts of hypochlorous acid during inflammation. While pharmacological MPO inhibition mitigates all indices of experimental colitis, no studies have corroborated the role of MPO using knockout (KO) models. Therefore, we investigated MPO deficient mice in a murine model of colitis. Wild …
Nutritional Support: The Use of Antioxidants in Inflammatory Bowel Disease
Publication Year: 2024 Source: Int J Mol Sci PMID: 38673974 DOI: 10.3390/ijms25084390
The problem of treating inflammatory bowel disease continues to be a topic of great interest for researchers. Despite the complexity surrounding their treatment and strategies to prolong periods of remission, there is a promising exploration of various compounds that have potential in combating inflammation and alleviating symptoms. Selenium, calcium, magnesium, …
Myeloid Cell-Derived IL-1 Signaling Damps Neuregulin-1 from Fibroblasts to Suppress Colitis-Induced Early Repair of the Intestinal Epithelium
Publication Year: 2024 Source: Int J Mol Sci PMID: 38674054
No Abstract
Research Progress on Anti-Inflammatory Effects and Related Mechanisms of Astragalin
Publication Year: 2024 Source: Int J Mol Sci PMID: 38674061
No Abstract
Aryl Hydrocarbon Receptor Signalling in the Control of Gut Inflammation
Publication Year: 2024 Source: Int J Mol Sci PMID: 38674118 DOI: 10.3390/ijms25084527
Aryl hydrocarbon receptor (AHR), a transcription factor activated by many natural and synthetic ligands, represents an important mediator of the interplay between the environment and the host's immune responses. In a healthy gut, AHR activation promotes tolerogenic signals, which help maintain mucosal homeostasis. AHR expression is defective in the inflamed …
Oxidative Stress-Responsive Apoptosis Inducing Protein (ORAIP) Plays a Critical Role in Dextran Sulfate Sodium-Induced Murine Model of Ulcerative Colitis
Publication Year: 2024 Source: Medicina (Kaunas) PMID: 38674185 DOI: 10.3390/medicina60040539
Oxidative stress is implicated in the pathogenesis of various acute disorders including ischemia/reperfusion injury, ultraviolet/radiation burn, as well as chronic disorders such as dyslipidemia, atherosclerosis, diabetes mellitus, chronic renal disease, and inflammatory bowel disease (IBD). However, the precise mechanism involved remains to be clarified. We formerly identified a novel apoptosis-inducing …
Extrachromosomal Circular DNA: An Emerging Potential Biomarker for Inflammatory Bowel Diseases?
Publication Year: 2024 Source: Genes (Basel) PMID: 38674347 DOI: 10.3390/genes15040414
Inflammatory bowel disease (IBD) comprising ulcerative colitis and Crohn's disease is a chronic immune-mediated disease which affects the gastrointestinal tract with a relapsing and remitting course, causing lifelong morbidity. IBD pathogenesis is determined by multiple factors including genetics, immune and microbial factors, and environmental factors. Although therapy options are expanding, …
The Modulatory Effects of Curcumin on the Gut Microbiota: A Potential Strategy for Disease Treatment and Health Promotion
Publication Year: 2024 Source: Microorganisms PMID: 38674587
No Abstract
Effect of Stool Sampling on a Routine Clinical Method for the Quantification of Six Short Chain Fatty Acids in Stool Using Gas Chromatography-Mass Spectrometry
Publication Year: 2024 Source: Microorganisms PMID: 38674773
No Abstract
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