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Kruppel-like factor 6 (KLF6) is a tumor-suppressor gene frequently inactivated in colorectal cancer

Publication Year: 2004 Source: Gastroenterology PMID: 15057748 DOI: 10.1053/j.gastro.2004.01.005

Inflammatory bowel diseases (IBD) are characterized by a sustained inflammatory cascade that gives rise to the release of mediators capable of degrading and modifying bowel wall structure. Our aims were (i) to measure the production of matrix metalloproteinase-3 (MMP-3), and its tissue inhibitor, tissue inhibitor of metalloproteinase-1 (TIMP-1), by inflamed …

Enamel matrix proteins in the treatment of intra-bony defects. A prospective 24-month clinical trial

Publication Year: 2004 Source: J Clin Periodontol PMID: 15058375 DOI: 10.1111/j.0303-6979.2004.00437.x

OBJECTIVES: Individuals with inflammatory bowel disease (IBD) are at increased risk for thrombosis and vitamin deficiencies. Low plasma levels of vitamin B(6) are an independent risk factor for thrombosis and may cause hyperhomocysteinemia, another recognized risk factor for thrombosis. The aim of this study was to evaluate vitamin B(6) plasma …

Regulation of gene expression in inflammatory bowel disease and correlation with IBD drugs: screening by DNA microarrays

Publication Year: 2004 Source: Inflamm Bowel Dis PMID: 15058520 DOI: 10.1097/00054725-200401000-00001

Comment in Inflamm Bowel Dis. 2002 Sep;8(5):373-4. OBJECTIVES: Quality of life is reduced in inflammatory bowel disease (IBD). Whether or not this is true in IBD patients in long-standing remission is unclear. Symptoms compatible with irritable bowel syndrome (IBS) are common in IBD patients in remission. The importance of psychological …

A genome scan in 260 inflammatory bowel disease-affected relative pairs

Publication Year: 2004 Source: Inflamm Bowel Dis PMID: 15058521 DOI: 10.1097/00054725-200401000-00002

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Colocolonic intussusception of a giant pseudopolyp in a patient with ulcerative colitis: a case report and review of the literature

Publication Year: 2004 Source: Inflamm Bowel Dis PMID: 15058526 DOI: 10.1097/00054725-200401000-00007

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Modern imaging using computer tomography and magnetic resonance imaging for inflammatory bowel disease (IBD) AU1

Publication Year: 2004 Source: Inflamm Bowel Dis PMID: 15058527 DOI: 10.1097/00054725-200401000-00008

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Immunohistochemical expression of cyclin D1, cyclin E, p21/waf1 and p27/kip1 in inflammatory bowel disease: correlation with other cell-cycle-related proteins (Rb, p53, ki-67 and PCNA) and clinicopathological features

Publication Year: 2004 Source: Int J Colorectal Dis PMID: 15060836 DOI: 10.1007/s00384-003-0571-3

BACKGROUND: There is a general lack of information on the care of inflammatory bowel disease (IBD) in a broad, geographically diverse, non-clinic population. The purposes of this study were (1) to compare a sample drawn from the membership of a national Crohn's and Colitis Foundation to published clinic-based and population-based …

The effect of dietary glutathione and coenzyme Q10 on the prevention and treatment of inflammatory bowel disease in mice

Publication Year: 2004 Source: Int J Vitam Nutr Res PMID: 15060903 DOI: 10.1024/0300-9831.74.1.74

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Primary sclerosing cholangitis

Publication Year: 2004 Source: Clin Liver Dis PMID: 15062201 DOI: 10.1016/S1089-3261(03)00127-2

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Probiotics in inflammatory bowel disease--therapeutic rationale and role

Publication Year: 2004 Source: Adv Drug Deliv Rev PMID: 15063591 DOI: 10.1016/j.addr.2003.11.003

The Haseman-Elston (HE) regression method offers a mathematically and computationally simpler alternative to variance-components (VC) models for the linkage analysis of quantitative traits. However, current versions of HE regression and VC models are not optimised for binary traits. Here, we present a modified HE regression and a liability-threshold VC model …

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